Aldol condensation over layered double hydroxides

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Aldol condensation over layered double hydroxides

Popis výsledku v původním jazyce

Aldol condensation is usually catalyzed by hydroxides, such as NaOH and Ca(OH)2, but their use leads to problems with wastewater treatments.1 For this reason, various solid base heterogeneous materials which can be separated from the reaction mixture and possibly reused, are studied.2 Layered double hydroxides (LDHs; synthetic analogues of hydrotalcites) are quite promising materials to catalyze such reaction. This work focuses on utilization of LDHs for aldol condensation of campholenic aldehyde (CA) with propanal or butanal. CA was prepared by α-pinene oxide isomerization with ZnBr2 (total conversion, 89% selectivity to CA, 70 °C, toluene). Prepared LDHs were characterized by various techniques (AAS, XRD, XRF etc.). The influence of reaction conditions (Mg:Al molar ratio, conditions of LDHs activation, presence of a modification component, reactants ratio, temperature etc.) on reaction course were studied in order to produce aldehydes I or II (Scheme 1). Subsequently these compounds can be hydrogenated to obtain fragrances like Levosandol and Brahmanol.

Název v anglickém jazyce

Aldol condensation over layered double hydroxides

Popis výsledku anglicky

Aldol condensation is usually catalyzed by hydroxides, such as NaOH and Ca(OH)2, but their use leads to problems with wastewater treatments.1 For this reason, various solid base heterogeneous materials which can be separated from the reaction mixture and possibly reused, are studied.2 Layered double hydroxides (LDHs; synthetic analogues of hydrotalcites) are quite promising materials to catalyze such reaction. This work focuses on utilization of LDHs for aldol condensation of campholenic aldehyde (CA) with propanal or butanal. CA was prepared by α-pinene oxide isomerization with ZnBr2 (total conversion, 89% selectivity to CA, 70 °C, toluene). Prepared LDHs were characterized by various techniques (AAS, XRD, XRF etc.). The influence of reaction conditions (Mg:Al molar ratio, conditions of LDHs activation, presence of a modification component, reactants ratio, temperature etc.) on reaction course were studied in order to produce aldehydes I or II (Scheme 1). Subsequently these compounds can be hydrogenated to obtain fragrances like Levosandol and Brahmanol.

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

10401 - Organic chemistry

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

PROCEEDINGS of the 6th International Conference on Chemical Technology

ISBN

978-80-86238-77-7

ISSN

2336-8128

e-ISSN

neuvedeno

Počet stran výsledku

4

Strana od-do

359-363

Název nakladatele

Česká společnost průmyslové chemie (ČSPCH)

Místo vydání

Praha

Místo konání akce

Mikulov

Datum konání akce

16. 4. 2018

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000461293800066