Homochiral metal-organic frameworks functionalized SERS substrate for atto-molar enantio-selective detection

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F20%3A43921243" target="_blank" >RIV/60461373:22310/20:43921243 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/44555601:13440/20:43895985

Výsledek na webu

<a href="https://doi.org/10.1016/j.apmt.2020.100666" target="_blank" >https://doi.org/10.1016/j.apmt.2020.100666</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.apmt.2020.100666" target="_blank" >10.1016/j.apmt.2020.100666</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Homochiral metal-organic frameworks functionalized SERS substrate for atto-molar enantio-selective detection

Popis výsledku v původním jazyce

In this work, the plasmon-active gold grating functionalized by homochiral metal-organic frameworks (HMOF) L- or D-MOF-6 was proposed as unprecedent tool for enantio-selective SERS-based discrimination. The gold grating surface possesses the homogeneous distribution of plasmon intensity along the active sample area, responsible for excitation of consistent SERS signal. L- and D- lactic acids enantiomers were used for the preparation of enantio-selective surface grafted MOF layer with opposite chiral-entrapping selectivity. The HMOFs films, grafted onto gold gratings provide the selective enantiomers entrapping from solution and contribute to the chemical enhancement of SERS. Obtained SERS substrates were able to selectively entrap the (R)-(+)- and (S)-(−)-methylphenylsulfoxide (model analyte) from solution and recognize them with atto-molecular concentration limits and perfect reproducubility. Moreover, the possibility of enantiomers detection and recognition in their mixtures was also demonstrated with similar recognition limits. The unprecedented detection and enantioselective recognition were further demonstrated on the biorelevant analytes, including complex sample.

Název v anglickém jazyce

Homochiral metal-organic frameworks functionalized SERS substrate for atto-molar enantio-selective detection

Popis výsledku anglicky

In this work, the plasmon-active gold grating functionalized by homochiral metal-organic frameworks (HMOF) L- or D-MOF-6 was proposed as unprecedent tool for enantio-selective SERS-based discrimination. The gold grating surface possesses the homogeneous distribution of plasmon intensity along the active sample area, responsible for excitation of consistent SERS signal. L- and D- lactic acids enantiomers were used for the preparation of enantio-selective surface grafted MOF layer with opposite chiral-entrapping selectivity. The HMOFs films, grafted onto gold gratings provide the selective enantiomers entrapping from solution and contribute to the chemical enhancement of SERS. Obtained SERS substrates were able to selectively entrap the (R)-(+)- and (S)-(−)-methylphenylsulfoxide (model analyte) from solution and recognize them with atto-molecular concentration limits and perfect reproducubility. Moreover, the possibility of enantiomers detection and recognition in their mixtures was also demonstrated with similar recognition limits. The unprecedented detection and enantioselective recognition were further demonstrated on the biorelevant analytes, including complex sample.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20501 - Materials engineering

Projekt

<a href="/cs/project/GA18-26170S" target="_blank" >GA18-26170S: Světlem laditelné konjugované polymery pro vratné spínání vodivosti</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Applied Materials Today

ISSN

2352-9407

e-ISSN

—

Svazek periodika

20

Číslo periodika v rámci svazku

SEP 2020

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

7

Strana od-do

"100666/1"-7

Kód UT WoS článku

000598346500015

EID výsledku v databázi Scopus

2-s2.0-85084263625