Electrochemically oxidized 15-crown-5 substituted thiophene and host-guest interaction with new psychoactive substances

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F21%3A43921601" target="_blank" >RIV/60461373:22310/21:43921601 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60461373:22330/21:43921601 RIV/60461373:22340/21:43921601 RIV/60461373:22810/21:43921601

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0013468621001523?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0013468621001523?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.electacta.2021.137862" target="_blank" >10.1016/j.electacta.2021.137862</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Electrochemically oxidized 15-crown-5 substituted thiophene and host-guest interaction with new psychoactive substances

Popis výsledku v původním jazyce

The aim of this work is to develop an impedimetric sensor using the principle of host- guest interaction for the detection of new psychoactive substances (NPSs). Synthesized 4 -( N -3- thiophenecarboxamido)benzo-15-crown-5 (TH3CA4AB15C5) was electrochemically deposited on the sur- face of a platinum disc electrode using cyclic voltammetry. Spectroscopic (infrared and NMR spec- troscopy) and electrochemical impedance spectroscopy (EIS) studies were applied to confirm the struc- ture of the polymeric film deposited onto the electrode surface and to evaluate its affinity towards 2- aminoindane (AI), 2-(methylamino)-1-phenylbutan-1-one (buphedrone, MABP) and 3 ,4 -methylenedioxy- α-pyrrolidinopropiophenone (MDPPP). These studies showed that the ease of formation hydrogen bonds between the product of electrochemical oxidation (TH3CA4AB15C5) and the above-mentioned analytes is the dominant factor for obtaining a useful analytical signal. The changes in the resistance to charge trans- fer obtained during the EIS measurements allowed: i ) to separately measure both the synthetic cathi- nones (MABP, MDPPP) and AI in the concentration range 1.99 x 10 –5 –1.22 x 10 –3 M; ii ) to quantify AI at levels of (1.6 –3.0) x 10 –4 M in the presence of various representatives from the NPS family.

Název v anglickém jazyce

Electrochemically oxidized 15-crown-5 substituted thiophene and host-guest interaction with new psychoactive substances

Popis výsledku anglicky

The aim of this work is to develop an impedimetric sensor using the principle of host- guest interaction for the detection of new psychoactive substances (NPSs). Synthesized 4 -( N -3- thiophenecarboxamido)benzo-15-crown-5 (TH3CA4AB15C5) was electrochemically deposited on the sur- face of a platinum disc electrode using cyclic voltammetry. Spectroscopic (infrared and NMR spec- troscopy) and electrochemical impedance spectroscopy (EIS) studies were applied to confirm the struc- ture of the polymeric film deposited onto the electrode surface and to evaluate its affinity towards 2- aminoindane (AI), 2-(methylamino)-1-phenylbutan-1-one (buphedrone, MABP) and 3 ,4 -methylenedioxy- α-pyrrolidinopropiophenone (MDPPP). These studies showed that the ease of formation hydrogen bonds between the product of electrochemical oxidation (TH3CA4AB15C5) and the above-mentioned analytes is the dominant factor for obtaining a useful analytical signal. The changes in the resistance to charge trans- fer obtained during the EIS measurements allowed: i ) to separately measure both the synthetic cathi- nones (MABP, MDPPP) and AI in the concentration range 1.99 x 10 –5 –1.22 x 10 –3 M; ii ) to quantify AI at levels of (1.6 –3.0) x 10 –4 M in the presence of various representatives from the NPS family.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Electrochimica Acta

ISSN

0013-4686

e-ISSN

—

Svazek periodika

373

Číslo periodika v rámci svazku

20 March 2021

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

9

Strana od-do

137862

Kód UT WoS článku

000621259000009

EID výsledku v databázi Scopus

2-s2.0-85100674172