Self-Propelled Multifunctional Microrobots Harboring Chiral Supramolecular Selectors for “Enantiorecognition-on-the-Fly”

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F22%3A43924079" target="_blank" >RIV/60461373:22310/22:43924079 - isvavai.cz</a>

Výsledek na webu

<a href="https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202116090" target="_blank" >https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202116090</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/anie.202116090" target="_blank" >10.1002/anie.202116090</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Self-Propelled Multifunctional Microrobots Harboring Chiral Supramolecular Selectors for “Enantiorecognition-on-the-Fly”

Popis výsledku v původním jazyce

Herein, a general procedure for the synthesis of multifunctional MRs, which simultaneously exhibit i) chiral, ii) magnetic, and iii) fluorescent properties in combination with iv) self-propulsion, is reported. Self-propelled Ni@Pt superparamagnetic microrockets have been functionalized with fluorescent CdS quantum dots carrying a chiral host biomolecule as β-cyclodextrin (β-CD). The “on-the-fly” chiral recognition potential of MRs has been interrogated by taking advantage of the β-CD affinity to supramolecularly accommodate different chiral biomolecules (i.e., amino acids). As a proof-of-concept, tryptophan enantiomers have been discriminated with a dual-mode (optical and electrochemical) readout. This approach paves the way to devise intelligent cargo micromachines with “built-in” chiral supramolecular recognition capabilities to elucidate the concept of “enantiorecognition-on-the-fly”, which might be facilely customized by tailoring the supramolecular host–guest encapsulation. © 2022 The Authors. Angewandte Chemie International Edition published by Wiley-VCH GmbH

Název v anglickém jazyce

Self-Propelled Multifunctional Microrobots Harboring Chiral Supramolecular Selectors for “Enantiorecognition-on-the-Fly”

Popis výsledku anglicky

Herein, a general procedure for the synthesis of multifunctional MRs, which simultaneously exhibit i) chiral, ii) magnetic, and iii) fluorescent properties in combination with iv) self-propulsion, is reported. Self-propelled Ni@Pt superparamagnetic microrockets have been functionalized with fluorescent CdS quantum dots carrying a chiral host biomolecule as β-cyclodextrin (β-CD). The “on-the-fly” chiral recognition potential of MRs has been interrogated by taking advantage of the β-CD affinity to supramolecularly accommodate different chiral biomolecules (i.e., amino acids). As a proof-of-concept, tryptophan enantiomers have been discriminated with a dual-mode (optical and electrochemical) readout. This approach paves the way to devise intelligent cargo micromachines with “built-in” chiral supramolecular recognition capabilities to elucidate the concept of “enantiorecognition-on-the-fly”, which might be facilely customized by tailoring the supramolecular host–guest encapsulation. © 2022 The Authors. Angewandte Chemie International Edition published by Wiley-VCH GmbH

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10405 - Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)

Projekt

—

Návaznosti

O - Projekt operacniho programu

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Angewandte Chemie-International Edition

ISSN

1433-7851

e-ISSN

1521-3773

Svazek periodika

61

Číslo periodika v rámci svazku

14

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

7

Strana od-do

nestrankovano

Kód UT WoS článku

000752944600001

EID výsledku v databázi Scopus

2-s2.0-85124569445