MONITORING THE INTERACTION OF SYNTHETIC HYDROXYAPATITES UNDER VARIED IN VITRO

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F23%3A43927498" target="_blank" >RIV/60461373:22310/23:43927498 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.ceramics-silikaty.cz/index.php?page=cs_detail_doi&id=1748" target="_blank" >https://www.ceramics-silikaty.cz/index.php?page=cs_detail_doi&id=1748</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.13168/cs.2023.0028" target="_blank" >10.13168/cs.2023.0028</a>

Jazyk výsledku

angličtina

Název v původním jazyce

MONITORING THE INTERACTION OF SYNTHETIC HYDROXYAPATITES UNDER VARIED IN VITRO

Popis výsledku v původním jazyce

The experimental work focuses on the detailed monitoring of the interaction of commercial hydroxyapatite (HA) granuleswith various morphologies and surfaces with simulated body fluid (SBF) under varied in vitro test conditions. The ISO23317:2014 standard, which specifies methods for the detection of apatite formation on the surface of materials in a simulated body fluid, mainly focuses on one-piece samples (tablets, rectangular shaped samples) under static conditions.The SBF solution modelling the inorganic part of blood plasma is buffered with a Tris buffer which can, under certainconditions, affect the in vitro test results by its own interaction with the tested material. Changes on the surfaces of the testedbioceramic granules with varied porosity and leachates from the buffered and unbuffered SBF solutions were characterised atselected time intervals using the available methods (SEM, BET, AAS, UV-VIS). The kinetics of the formation and morphologyof the precipitated hydroxyapatite (HAp) was found to vary under different in vitro test conditions. The leachates from thesolutions confirmed different rates of calcium and phosphate ions depletion, especially at the beginning of the assay. The pHanalyses of the buffered and unbuffered SBF solutions also showed a Tris buffer effect

Název v anglickém jazyce

MONITORING THE INTERACTION OF SYNTHETIC HYDROXYAPATITES UNDER VARIED IN VITRO

Popis výsledku anglicky

The experimental work focuses on the detailed monitoring of the interaction of commercial hydroxyapatite (HA) granuleswith various morphologies and surfaces with simulated body fluid (SBF) under varied in vitro test conditions. The ISO23317:2014 standard, which specifies methods for the detection of apatite formation on the surface of materials in a simulated body fluid, mainly focuses on one-piece samples (tablets, rectangular shaped samples) under static conditions.The SBF solution modelling the inorganic part of blood plasma is buffered with a Tris buffer which can, under certainconditions, affect the in vitro test results by its own interaction with the tested material. Changes on the surfaces of the testedbioceramic granules with varied porosity and leachates from the buffered and unbuffered SBF solutions were characterised atselected time intervals using the available methods (SEM, BET, AAS, UV-VIS). The kinetics of the formation and morphologyof the precipitated hydroxyapatite (HAp) was found to vary under different in vitro test conditions. The leachates from thesolutions confirmed different rates of calcium and phosphate ions depletion, especially at the beginning of the assay. The pHanalyses of the buffered and unbuffered SBF solutions also showed a Tris buffer effect

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20504 - Ceramics

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

CERAMICS-SILIKATY

ISSN

0862-5468

e-ISSN

1804-5847

Svazek periodika

67

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

9

Strana od-do

282-290

Kód UT WoS článku

001069725600001

EID výsledku v databázi Scopus

2-s2.0-85172873375