Antibacterial properties of Polytetrafluorethylene Nanotextile with Ag Nanoparticles Induced By High-Energy Excimer Laser

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F23%3A43927741" target="_blank" >RIV/60461373:22310/23:43927741 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Antibacterial properties of Polytetrafluorethylene Nanotextile with Ag Nanoparticles Induced By High-Energy Excimer Laser

Popis výsledku v původním jazyce

In presented study, we focused on modification of porous PTFE nanotextile by sputtering of thin silver nanolayers and subsequent induction of silver nanoparticle formation by single-shot pulse of KrF excimer laser. The changes in surface morphology were studied and while the pristine PTFE substrate exhibited only minor changes due to excimer laser exposure, significant changes have been observed on the silver sputtered PTFE surfaces. Applying excimer laser led to formation of silver nanoparticles and wettability very close to that of a superhydrophobic surface was measured on created PTFE-Ag composite. Formation of superposed globular structures on the PTFE lamellar primary structure was confirmed by both scanning electron microscopy (SEM) and atomic force microscopy (AFM) . Combination of changes in surface morphology, chemistry and wettability induced significant change in PTFE antibacterial properties. PTFE nanotextile samples coated with silver and further treated with excimer laser 150 mJ/cm2 inhibited 100 % of Gram-negative E. coli bacterial strain. The motivation behind this study was to fabricate flexible and elastic material with hydrophobic character and antibacterial properties, that can be used in different types of applications, mainly in tissue engineering and the medicinal industry. The successful silver enhancement of PTFE surfaces thus shows promise in use for instance as antibacterial implant coatings or as supportive scaffolds for growth of bone cells and tissues.

Název v anglickém jazyce

Antibacterial properties of Polytetrafluorethylene Nanotextile with Ag Nanoparticles Induced By High-Energy Excimer Laser

Popis výsledku anglicky

In presented study, we focused on modification of porous PTFE nanotextile by sputtering of thin silver nanolayers and subsequent induction of silver nanoparticle formation by single-shot pulse of KrF excimer laser. The changes in surface morphology were studied and while the pristine PTFE substrate exhibited only minor changes due to excimer laser exposure, significant changes have been observed on the silver sputtered PTFE surfaces. Applying excimer laser led to formation of silver nanoparticles and wettability very close to that of a superhydrophobic surface was measured on created PTFE-Ag composite. Formation of superposed globular structures on the PTFE lamellar primary structure was confirmed by both scanning electron microscopy (SEM) and atomic force microscopy (AFM) . Combination of changes in surface morphology, chemistry and wettability induced significant change in PTFE antibacterial properties. PTFE nanotextile samples coated with silver and further treated with excimer laser 150 mJ/cm2 inhibited 100 % of Gram-negative E. coli bacterial strain. The motivation behind this study was to fabricate flexible and elastic material with hydrophobic character and antibacterial properties, that can be used in different types of applications, mainly in tissue engineering and the medicinal industry. The successful silver enhancement of PTFE surfaces thus shows promise in use for instance as antibacterial implant coatings or as supportive scaffolds for growth of bone cells and tissues.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

20506 - Coating and films

Projekt

<a href="/cs/project/NU20-08-00208" target="_blank" >NU20-08-00208: Nové vaskularizované konstrukty na bázi kmenových buněk pro inženýrství měkkých a tvrdých tkání</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů