Montmorillonite—environmentally friendly catalyst for esterification of carvacrol with acetic anhydride

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F25%3A43931544" target="_blank" >RIV/60461373:22310/25:43931544 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/article/10.1007/s11144-025-02859-3" target="_blank" >https://link.springer.com/article/10.1007/s11144-025-02859-3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11144-025-02859-3" target="_blank" >10.1007/s11144-025-02859-3</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Montmorillonite—environmentally friendly catalyst for esterification of carvacrol with acetic anhydride

Popis výsledku v původním jazyce

Carvacryl acetate (5-isopropyl-2-methylphenyl acetate) is a monoterpenoid ester, which is characterized by similar or even higher pharmacological properties as its precursor—carvacrol, including anti-inflammatory, antibacterial, antinociceptive activity. Traditional synthesis of carvacryl acetate is the reaction of carvacrol with acetyl chloride or acetic anhydride using homogeneous basic catalyst. Such homogeneous reaction arrangement suffers from the necessity of ester isolation from homogeneous catalyst together with formation of a significant amount of chlorinated waste (in case of acetyl chloride use). In our work we present solvent—free synthesis of carvacryl acetate with acetic anhydride using a cheap, eco-friendly and available heterogeneous catalyst—montmorillonite K10, which was used as commercially available or in acid treated (nitric or sulfuric acid) form. Prepared acid treated montmorillonites were thoroughly characterized (XRD, XRF, nitrogen physisorption, static laser light scattering, FTIR) and its acidity was studied using temperature programmed desorption of pyridine and DR–UV–Vis spectroscopy. In the case of using montmorillonite treated with sulfuric or nitric acid as catalyst total conversion of carvacrol after 10–15 min of reaction at room temperature was observed (100% selectivity to the desired ester). Reaction kinetic parameters were evaluated using ERA3.0 software package.

Název v anglickém jazyce

Montmorillonite—environmentally friendly catalyst for esterification of carvacrol with acetic anhydride

Popis výsledku anglicky

Carvacryl acetate (5-isopropyl-2-methylphenyl acetate) is a monoterpenoid ester, which is characterized by similar or even higher pharmacological properties as its precursor—carvacrol, including anti-inflammatory, antibacterial, antinociceptive activity. Traditional synthesis of carvacryl acetate is the reaction of carvacrol with acetyl chloride or acetic anhydride using homogeneous basic catalyst. Such homogeneous reaction arrangement suffers from the necessity of ester isolation from homogeneous catalyst together with formation of a significant amount of chlorinated waste (in case of acetyl chloride use). In our work we present solvent—free synthesis of carvacryl acetate with acetic anhydride using a cheap, eco-friendly and available heterogeneous catalyst—montmorillonite K10, which was used as commercially available or in acid treated (nitric or sulfuric acid) form. Prepared acid treated montmorillonites were thoroughly characterized (XRD, XRF, nitrogen physisorption, static laser light scattering, FTIR) and its acidity was studied using temperature programmed desorption of pyridine and DR–UV–Vis spectroscopy. In the case of using montmorillonite treated with sulfuric or nitric acid as catalyst total conversion of carvacrol after 10–15 min of reaction at room temperature was observed (100% selectivity to the desired ester). Reaction kinetic parameters were evaluated using ERA3.0 software package.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10403 - Physical chemistry

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Reaction Kinetics Mechanisms and Catalysis

ISSN

1878-5190

e-ISSN

1878-5204

Svazek periodika

138

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

13

Strana od-do

"2025–2037"

Kód UT WoS článku

001488987100001

EID výsledku v databázi Scopus

2-s2.0-105005098764