Peak bordering for ultrafast single particle analysis using ICP-MS

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F19%3A43917837" target="_blank" >RIV/60461373:22330/19:43917837 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60461373:22340/19:43917837

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0039914019300323?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0039914019300323?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.talanta.2019.01.030" target="_blank" >10.1016/j.talanta.2019.01.030</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Peak bordering for ultrafast single particle analysis using ICP-MS

Popis výsledku v původním jazyce

The characterisation of inorganic nanoparticles (NPs) by single particle inductively coupled plasma mass spectroscopy is possible only if the spectrometer is capable of measurement with high time-signal resolution. The latest generation of spectrometers allow for measurements with dwell times (dt) shorter than the 100 mu s gold standard, i.e. as low as 10 mu s. The statistical behaviours of signals obtained with dt values of 10, 20, 50, and 100 mu s were tested for 40, 60, and 100 nm silver NPs. Very low measured signals (units of counts) led to the occurrence of zero signal values inside the peaks corresponding to individual NPs. The probability of the occurrence of a zero signal inside the peak increased with decreasing dt and decreasing NP size. The standard approach to the bordering of the beginning and end of the peak by one zero signal point failed here and lead to the false detection of a larger number of smaller peaks. For example, in the case of 40 nm NPs a quadruple number of peaks were detected for a dt value of 10 mu s compared to the 100 mu s dt value; the mean peak width at 10 mu s dt was approximately 220 mu s, while at 100 mu s dt it was 550 mu s. The results tended to be less distorted when dt was longer and the NP size was larger. Low dt values also led to a distortion of the peak area distribution. For 40 nm NPs and 10 mu s, the most frequent peak area and the width of the peak area distribution were not evaluated due to a non-Gaussian course; 20 mu s dt caused (compared to 100 mu s) a decrease in the most frequent peak area by approximately 35% (33 counts for 100 mu s dt vs. 22 counts for 20 mu s dt) and an increase in the width of the peak area distribution by 70% (10 counts for 100 mu s dt vs. 17 counts for 20 mu s dt). Therefore, new approaches to bordering peaks were tested, which consisted of searching for an uninterrupted zero signal point sequence with a total length of 50 mu s or 100 mu s. Only the criterion of a 100 mu s delay between the two adjacent peaks resulted in values of the number of detected peaks, the most frequent peak areas, and the width of peak area distribution virtually independent of dt.

Název v anglickém jazyce

Peak bordering for ultrafast single particle analysis using ICP-MS

Popis výsledku anglicky

The characterisation of inorganic nanoparticles (NPs) by single particle inductively coupled plasma mass spectroscopy is possible only if the spectrometer is capable of measurement with high time-signal resolution. The latest generation of spectrometers allow for measurements with dwell times (dt) shorter than the 100 mu s gold standard, i.e. as low as 10 mu s. The statistical behaviours of signals obtained with dt values of 10, 20, 50, and 100 mu s were tested for 40, 60, and 100 nm silver NPs. Very low measured signals (units of counts) led to the occurrence of zero signal values inside the peaks corresponding to individual NPs. The probability of the occurrence of a zero signal inside the peak increased with decreasing dt and decreasing NP size. The standard approach to the bordering of the beginning and end of the peak by one zero signal point failed here and lead to the false detection of a larger number of smaller peaks. For example, in the case of 40 nm NPs a quadruple number of peaks were detected for a dt value of 10 mu s compared to the 100 mu s dt value; the mean peak width at 10 mu s dt was approximately 220 mu s, while at 100 mu s dt it was 550 mu s. The results tended to be less distorted when dt was longer and the NP size was larger. Low dt values also led to a distortion of the peak area distribution. For 40 nm NPs and 10 mu s, the most frequent peak area and the width of the peak area distribution were not evaluated due to a non-Gaussian course; 20 mu s dt caused (compared to 100 mu s) a decrease in the most frequent peak area by approximately 35% (33 counts for 100 mu s dt vs. 22 counts for 20 mu s dt) and an increase in the width of the peak area distribution by 70% (10 counts for 100 mu s dt vs. 17 counts for 20 mu s dt). Therefore, new approaches to bordering peaks were tested, which consisted of searching for an uninterrupted zero signal point sequence with a total length of 50 mu s or 100 mu s. Only the criterion of a 100 mu s delay between the two adjacent peaks resulted in values of the number of detected peaks, the most frequent peak areas, and the width of peak area distribution virtually independent of dt.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

<a href="/cs/project/GA17-00291S" target="_blank" >GA17-00291S: Charakterizace anorganických nanočástic pomocí ultrarychlé hmotnostní spektrometrie s indukčně vázaným plazmatem</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Talanta

ISSN

0039-9140

e-ISSN

—

Svazek periodika

197

Číslo periodika v rámci svazku

MAY 15 2019

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

10

Strana od-do

189-198

Kód UT WoS článku

000460710200025

EID výsledku v databázi Scopus

2-s2.0-85059812327