Recent Achievements in Medicinal and Supramolecular Chemistry of Betulinic Acid and Its Derivatives
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F19%3A43918007" target="_blank" >RIV/60461373:22330/19:43918007 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/61389030:_____/19:00509279
Výsledek na webu
<a href="https://www.mdpi.com/1420-3049/24/19/3546" target="_blank" >https://www.mdpi.com/1420-3049/24/19/3546</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/molecules24193546" target="_blank" >10.3390/molecules24193546</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Recent Achievements in Medicinal and Supramolecular Chemistry of Betulinic Acid and Its Derivatives
Popis výsledku v původním jazyce
The subject of this review article refers to the recent achievements in the investigation of pharmacological activity and supramolecular characteristics of betulinic acid and its diverse derivatives, with special focus on their cytotoxic effect, antitumor activity, and antiviral effect, and mostly covers a period 2015-2018. Literature sources published earlier are referred to in required coherences or from historical points of view. Relationships between pharmacological activity and supramolecular characteristics are included if such investigation has been done in the original literature sources. A wide practical applicability of betulinic acid and its derivatives demonstrated in the literature sources is also included in this review article. Several literature sources also focused on in silico calculation of physicochemical and ADME parameters of the developed compounds, and on a comparison between the experimental and calculated data.
Název v anglickém jazyce
Recent Achievements in Medicinal and Supramolecular Chemistry of Betulinic Acid and Its Derivatives
Popis výsledku anglicky
The subject of this review article refers to the recent achievements in the investigation of pharmacological activity and supramolecular characteristics of betulinic acid and its diverse derivatives, with special focus on their cytotoxic effect, antitumor activity, and antiviral effect, and mostly covers a period 2015-2018. Literature sources published earlier are referred to in required coherences or from historical points of view. Relationships between pharmacological activity and supramolecular characteristics are included if such investigation has been done in the original literature sources. A wide practical applicability of betulinic acid and its derivatives demonstrated in the literature sources is also included in this review article. Several literature sources also focused on in silico calculation of physicochemical and ADME parameters of the developed compounds, and on a comparison between the experimental and calculated data.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10401 - Organic chemistry
Návaznosti výsledku
Projekt
Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2019
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Molecules
ISSN
1420-3049
e-ISSN
—
Svazek periodika
24
Číslo periodika v rámci svazku
19
Stát vydavatele periodika
CH - Švýcarská konfederace
Počet stran výsledku
20
Strana od-do
—
Kód UT WoS článku
000496242300131
EID výsledku v databázi Scopus
2-s2.0-85072762176