Towards a dietary-exposome assessment of chemicals in food: An update on the chronic health risks for the European consumer

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F19%3A43918888" target="_blank" >RIV/60461373:22330/19:43918888 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.tandfonline.com/doi/pdf/10.1080/10408398.2019.1612320?needAccess=true&" target="_blank" >https://www.tandfonline.com/doi/pdf/10.1080/10408398.2019.1612320?needAccess=true&</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/10408398.2019.1612320" target="_blank" >10.1080/10408398.2019.1612320</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Towards a dietary-exposome assessment of chemicals in food: An update on the chronic health risks for the European consumer

Popis výsledku v původním jazyce

An informed opinion to a hugely important question, whether the food on the Europeans&apos; plate is safe to eat, is provided. Today, the Europeans face food-borne health risks from non-communicable diseases induced by excess body weight, outbreaks caused by pathogens, antimicrobial resistance and exposures to chemical contaminants. In this review, these risks are first put in an order of importance. Then, not only potentially injurious dietary chemicals are discussed but also beneficial factors of the food. This review can be regarded as an attempt towards a dietary-exposome evaluation of the chemicals, the average European adult consumers could chronically expose to during their life-times. Risk ranking reveals that currently the European adults are chronically exposed to a mixture of potentially genotoxic-carcinogenic contaminants, particularly food process contaminants, at the potential risk levels. Furthermore, several of the contaminants whose dietary exposures pose risks appear to be carcinogens operating with a genotoxic mode of action targeting the liver. This suggests that combined health risks from the exposure to a mixture of the chemical contaminants poses a greater potential risk than the risks assessed for single compounds. Over 100 European-level risk assessments are examined. Finally, the importance of a diversified and balanced diet is emphasized.

Název v anglickém jazyce

Towards a dietary-exposome assessment of chemicals in food: An update on the chronic health risks for the European consumer

Popis výsledku anglicky

An informed opinion to a hugely important question, whether the food on the Europeans&apos; plate is safe to eat, is provided. Today, the Europeans face food-borne health risks from non-communicable diseases induced by excess body weight, outbreaks caused by pathogens, antimicrobial resistance and exposures to chemical contaminants. In this review, these risks are first put in an order of importance. Then, not only potentially injurious dietary chemicals are discussed but also beneficial factors of the food. This review can be regarded as an attempt towards a dietary-exposome evaluation of the chemicals, the average European adult consumers could chronically expose to during their life-times. Risk ranking reveals that currently the European adults are chronically exposed to a mixture of potentially genotoxic-carcinogenic contaminants, particularly food process contaminants, at the potential risk levels. Furthermore, several of the contaminants whose dietary exposures pose risks appear to be carcinogens operating with a genotoxic mode of action targeting the liver. This suggests that combined health risks from the exposure to a mixture of the chemical contaminants poses a greater potential risk than the risks assessed for single compounds. Over 100 European-level risk assessments are examined. Finally, the importance of a diversified and balanced diet is emphasized.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30304 - Public and environmental health

Projekt

—

Návaznosti

R - Projekt Ramcoveho programu EK

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

ISSN

1040-8398

e-ISSN

—

Svazek periodika

Neuveden

Číslo periodika v rámci svazku

MAY 2019

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

22

Strana od-do

1-22

Kód UT WoS článku

000469585300001

EID výsledku v databázi Scopus

2-s2.0-85073802563