Disrupted actin: a novel player in pathogen attack sensing?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F20%3A43921182" target="_blank" >RIV/60461373:22330/20:43921182 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61389030:_____/20:00540536 RIV/00216208:11310/20:10413434

Výsledek na webu

<a href="https://nph.onlinelibrary.wiley.com/doi/full/10.1111/nph.16584" target="_blank" >https://nph.onlinelibrary.wiley.com/doi/full/10.1111/nph.16584</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/nph.16584" target="_blank" >10.1111/nph.16584</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Disrupted actin: a novel player in pathogen attack sensing?

Popis výsledku v původním jazyce

The actin cytoskeleton is widely involved in plant immune responses. The majority of studies show that chemical disruption of the actin cytoskeleton increases plant susceptibility to pathogen infection. Similarly, several pathogens have adopted this as a virulence strategy and produce effectors that affect cytoskeleton integrity. Such effectors either exhibit actin-depolymerizing activity themselves or prevent actin polymerization. Is it thus possible for plants to recognize the actin&apos;s status and launch a counterattack? Recently we showed that chemical depolymerization of actin filaments can trigger resistance to further infection via the specific activation of salicylic acid (SA) signalling. This is accompanied by several defence-related, but SA-independent, effects (e.g. callose deposition, gene expression), relying on vesicular trafficking and phospholipid metabolism. These data suggest that the role of actin in plant-pathogen interactions is more complex than previously believed. It raises the question of whether plants have evolved a mechanism of sensing pathological actin disruption that eventually triggers defence responses. If so, what is the molecular basis of it? Otherwise, why does actin depolymerization specifically influence SA content but not any other phytohormone? Here we propose an updated model of actin&apos;s role in plant-microbe interactions and suggest some future directions of research to be conducted in this area.

Název v anglickém jazyce

Disrupted actin: a novel player in pathogen attack sensing?

Popis výsledku anglicky

The actin cytoskeleton is widely involved in plant immune responses. The majority of studies show that chemical disruption of the actin cytoskeleton increases plant susceptibility to pathogen infection. Similarly, several pathogens have adopted this as a virulence strategy and produce effectors that affect cytoskeleton integrity. Such effectors either exhibit actin-depolymerizing activity themselves or prevent actin polymerization. Is it thus possible for plants to recognize the actin&apos;s status and launch a counterattack? Recently we showed that chemical depolymerization of actin filaments can trigger resistance to further infection via the specific activation of salicylic acid (SA) signalling. This is accompanied by several defence-related, but SA-independent, effects (e.g. callose deposition, gene expression), relying on vesicular trafficking and phospholipid metabolism. These data suggest that the role of actin in plant-pathogen interactions is more complex than previously believed. It raises the question of whether plants have evolved a mechanism of sensing pathological actin disruption that eventually triggers defence responses. If so, what is the molecular basis of it? Otherwise, why does actin depolymerization specifically influence SA content but not any other phytohormone? Here we propose an updated model of actin&apos;s role in plant-microbe interactions and suggest some future directions of research to be conducted in this area.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10611 - Plant sciences, botany

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

NEW PHYTOLOGIST

ISSN

0028-646X

e-ISSN

—

Svazek periodika

227

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

1605-1609

Kód UT WoS článku

000531904600001

EID výsledku v databázi Scopus

2-s2.0-85084501886