Investigation of Iris versicolor metabolic profile and optimization of the isolation of bioactive components on a semi-operation scale
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F24%3A43929746" target="_blank" >RIV/60461373:22330/24:43929746 - isvavai.cz</a>
Výsledek na webu
<a href="https://www.sciencedirect.com/science/article/pii/S1359511324002228?via%3Dihub#sec0070" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1359511324002228?via%3Dihub#sec0070</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.procbio.2024.07.001" target="_blank" >10.1016/j.procbio.2024.07.001</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Investigation of Iris versicolor metabolic profile and optimization of the isolation of bioactive components on a semi-operation scale
Popis výsledku v původním jazyce
In this study, we aimed to (i) better understand the phytochemical composition of extracts prepared from the leaves and roots with rhizomes of the scarcely studied Iris versicolor, and (ii) propose optimal extraction conditions (solvent composition, temperature, time) for the isolation of bioactive compounds. A UHPLC-QTOF-MS/MS targeted screening method was applied in combination with in silico fragmentation. The analysis revealed a total of 106 target metabolites, many of which are reported to occur in I. versicolor for the first time. (Iso)flavonoids were the most abundant compounds, followed by terpenoids, phenols, xanthones, phenolic acids, quinones, and steroids, with quinones being reported for the first time in this species. Terpenoids were characteristic of roots with rhizomes, while xanthones dominated in the leaves. Based on the varied experimental conditions, surface response analysis generated significant models for the extraction of terpenoids, quinones, and steroids. Our research provides valuable insight for the effective medicinal and commercial use of I. versicolor. © 2024
Název v anglickém jazyce
Investigation of Iris versicolor metabolic profile and optimization of the isolation of bioactive components on a semi-operation scale
Popis výsledku anglicky
In this study, we aimed to (i) better understand the phytochemical composition of extracts prepared from the leaves and roots with rhizomes of the scarcely studied Iris versicolor, and (ii) propose optimal extraction conditions (solvent composition, temperature, time) for the isolation of bioactive compounds. A UHPLC-QTOF-MS/MS targeted screening method was applied in combination with in silico fragmentation. The analysis revealed a total of 106 target metabolites, many of which are reported to occur in I. versicolor for the first time. (Iso)flavonoids were the most abundant compounds, followed by terpenoids, phenols, xanthones, phenolic acids, quinones, and steroids, with quinones being reported for the first time in this species. Terpenoids were characteristic of roots with rhizomes, while xanthones dominated in the leaves. Based on the varied experimental conditions, surface response analysis generated significant models for the extraction of terpenoids, quinones, and steroids. Our research provides valuable insight for the effective medicinal and commercial use of I. versicolor. © 2024
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10406 - Analytical chemistry
Návaznosti výsledku
Projekt
Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2024
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
PROCESS BIOCHEMISTRY
ISSN
1359-5113
e-ISSN
—
Svazek periodika
146
Číslo periodika v rámci svazku
neuveden
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
12
Strana od-do
97-108
Kód UT WoS článku
001275592700001
EID výsledku v databázi Scopus
2-s2.0-85198950062