Oligopyrrolické makrocykly substituované nukleosidy a nukleobázemi

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F04%3A00011125" target="_blank" >RIV/60461373:22340/04:00011125 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60461373:22340/04:00013193

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Nucleoside- and Nucleobase-Substituted Oligopyrrolic Macrocycles

Popis výsledku v původním jazyce

This chapter summarizes the design and synthesis of conjugates resulting from the combination of nucleic acid base derivatives, particularly nucleosides and nucleotides, with oligopyrrole macrocycles. In addition to detailing the methods of preparation and fundamental chemical properties, the vision behind such projects and the various applications targeted for use by these conjugates are also described. These systems combine into one chemical entity two of the more important biological building blocksfound in Nature, namely, nucleic acid bases (nucleobases) and porphyrins, and this leads to new constructs with rather unique chemical features as well as novel molecular recognition properties. Although the focus of the present chapter will be on systems containing natural nucleobase components, it is important to appreciate that the porphyrin portion of these constructs can include a range of synthetic oligopyrrole macrocycles that have no biological equivalent. This gives rise to prod

Název v anglickém jazyce

Nucleoside- and Nucleobase-Substituted Oligopyrrolic Macrocycles

Popis výsledku anglicky

This chapter summarizes the design and synthesis of conjugates resulting from the combination of nucleic acid base derivatives, particularly nucleosides and nucleotides, with oligopyrrole macrocycles. In addition to detailing the methods of preparation and fundamental chemical properties, the vision behind such projects and the various applications targeted for use by these conjugates are also described. These systems combine into one chemical entity two of the more important biological building blocksfound in Nature, namely, nucleic acid bases (nucleobases) and porphyrins, and this leads to new constructs with rather unique chemical features as well as novel molecular recognition properties. Although the focus of the present chapter will be on systems containing natural nucleobase components, it is important to appreciate that the porphyrin portion of these constructs can include a range of synthetic oligopyrrole macrocycles that have no biological equivalent. This gives rise to prod

Druh

C - Kapitola v odborné knize

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

<a href="/cs/project/GA203%2F02%2F0420" target="_blank" >GA203/02/0420: Tetrapyrrolové metalokomplexy: Modifikace triplexových struktur nukleových kyselin</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2004

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Dekker Encyclopedia of Nanoscience and Nanotechnology

ISBN

0-8247-4797-6

Počet stran výsledku

18

Strana od-do

2721-2738

Počet stran knihy

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Název nakladatele

Marcel Dekker AG

Místo vydání

Basel

Kód UT WoS kapitoly

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