Lower Retinol as an Independent Predictor of Mortality in Long-term Hemodialysis Patients: A Prospective Observational Cohort Study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F10%3A00023495" target="_blank" >RIV/60461373:22340/10:00023495 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Lower Retinol as an Independent Predictor of Mortality in Long-term Hemodialysis Patients: A Prospective Observational Cohort Study

Popis výsledku v původním jazyce

Background: Malnutrition, inflammation, and oxidative stress are inter-related mechanisms linked to the progression of cardiovascular disease and prognosis of long-term hemodialysis (HD) patients. In this study, we focus on antioxidant vitamins and traceelements and the relationship of their serum levels to the prognosis of long-term HD patients. Study Design: Prospective observational cohort study. Setting & Participants: 261 long-term HD patients prospectively followed up for 5 years (2003-2008). Thecontrol group consisted of 66 healthy participants. Predictors: Retinol, alpha-tocopherol, retinol-binding protein 4 (RBP-4), and the trace elements zinc and selenium. Outcomes: Mortality and cardiovascular mortality. During follow-up, 146 patients (56%) died, and for 71 of these, death was due to cardiovascular causes. Measurements: Retinol, alpha -tocopherol, RBP-4, zinc, selenium, and basic nutritional and inflammatory parameters measured at the beginning of the study. Results: Retin

Název v anglickém jazyce

Lower Retinol as an Independent Predictor of Mortality in Long-term Hemodialysis Patients: A Prospective Observational Cohort Study

Popis výsledku anglicky

Background: Malnutrition, inflammation, and oxidative stress are inter-related mechanisms linked to the progression of cardiovascular disease and prognosis of long-term hemodialysis (HD) patients. In this study, we focus on antioxidant vitamins and traceelements and the relationship of their serum levels to the prognosis of long-term HD patients. Study Design: Prospective observational cohort study. Setting & Participants: 261 long-term HD patients prospectively followed up for 5 years (2003-2008). Thecontrol group consisted of 66 healthy participants. Predictors: Retinol, alpha-tocopherol, retinol-binding protein 4 (RBP-4), and the trace elements zinc and selenium. Outcomes: Mortality and cardiovascular mortality. During follow-up, 146 patients (56%) died, and for 71 of these, death was due to cardiovascular causes. Measurements: Retinol, alpha -tocopherol, RBP-4, zinc, selenium, and basic nutritional and inflammatory parameters measured at the beginning of the study. Results: Retin

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

—

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

American Journal of Kidney Diseases

ISSN

0272-6386

e-ISSN

—

Svazek periodika

56

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

—

Kód UT WoS článku

000281203200014

EID výsledku v databázi Scopus

—