Hybrid SiO2 stimuli-responsive microparticles

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Hybrid SiO2 stimuli-responsive microparticles

Popis výsledku v původním jazyce

The possibility to control the release of active substances represents one of the most important attributes of targeted drug delivery (TDD). The purpose of this work is to design and characterize microscopic, synthetically created particles from composite material based on silica, thermoresponsive polymer poly-N-isopropylacrylamide (PNIPAM, LCST 32°C) and magnetite nanoparticles, which could be used as a means of such delivery. All of the materials mentioned above provide desired microparticles with unique characteristics such as endurance and hardness of silica, the ability of thermoresponsive polymers to change its volume in dependence on temperature and the possibility of induction heating as a result of the presence of magnetite nanoparticles. By combining these attributes, the final microparticles can act as the vessel for TDD able to transport the delivered substance into its destination an then release it there as a reaction to an external stimulus being the application of alter

Název v anglickém jazyce

Hybrid SiO2 stimuli-responsive microparticles

Popis výsledku anglicky

The possibility to control the release of active substances represents one of the most important attributes of targeted drug delivery (TDD). The purpose of this work is to design and characterize microscopic, synthetically created particles from composite material based on silica, thermoresponsive polymer poly-N-isopropylacrylamide (PNIPAM, LCST 32°C) and magnetite nanoparticles, which could be used as a means of such delivery. All of the materials mentioned above provide desired microparticles with unique characteristics such as endurance and hardness of silica, the ability of thermoresponsive polymers to change its volume in dependence on temperature and the possibility of induction heating as a result of the presence of magnetite nanoparticles. By combining these attributes, the final microparticles can act as the vessel for TDD able to transport the delivered substance into its destination an then release it there as a reaction to an external stimulus being the application of alter

Druh

D - Stať ve sborníku

CEP obor

CI - Průmyslová chemie a chemické inženýrství

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

CHOBOTIX 2012

ISBN

978-80-7080-813-9

ISSN

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e-ISSN

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Počet stran výsledku

6

Strana od-do

42-47

Název nakladatele

ICT Press, VŠCHT Praha

Místo vydání

Praha

Místo konání akce

Praha

Datum konání akce

10. 5. 2012

Typ akce podle státní příslušnosti

CST - Celostátní akce

Kód UT WoS článku

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