Three-phase slug flow in microchips can provide beneficial reaction conditions for enzyme liquid-liquid reactions

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F13%3A43895780" target="_blank" >RIV/60461373:22340/13:43895780 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/49777513:23640/13:43919660

Výsledek na webu

<a href="http://scitation.aip.org/content/aip/journal/bmf/7/5/10.1063/1.4821168" target="_blank" >http://scitation.aip.org/content/aip/journal/bmf/7/5/10.1063/1.4821168</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1063/1.4821168" target="_blank" >10.1063/1.4821168</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Three-phase slug flow in microchips can provide beneficial reaction conditions for enzyme liquid-liquid reactions

Popis výsledku v původním jazyce

Here, we introduce a solution to low stability of a two-phase slug flow with a chemical reaction occurring at the phase interface in a microfluidic reactor where substantial merging of individual reacting slugs results in the loss of uniformity of the flow. We create a three-phase slug flow by introducing a third fluid phase into the originally two-phase liquid-liquid slug flow, which generates small two-phase liquid slugs separated by gas phase. Introduction of the third phase into our system efficiently prevents merging of slugs and provides beneficial reaction conditions, such as uniform flow pattern along the whole reaction capillary, interfacial area with good reproducibility, and intensive water-oil interface renewal. We tested the three-phase flow on an enzyme hydrolysis of soybean oil and compared the reaction conversion with those from unstable two-phase slug flows. We experimentally confirmed that the three-phase slug flow arrangement provides conversions and pressure drops c

Název v anglickém jazyce

Three-phase slug flow in microchips can provide beneficial reaction conditions for enzyme liquid-liquid reactions

Popis výsledku anglicky

Here, we introduce a solution to low stability of a two-phase slug flow with a chemical reaction occurring at the phase interface in a microfluidic reactor where substantial merging of individual reacting slugs results in the loss of uniformity of the flow. We create a three-phase slug flow by introducing a third fluid phase into the originally two-phase liquid-liquid slug flow, which generates small two-phase liquid slugs separated by gas phase. Introduction of the third phase into our system efficiently prevents merging of slugs and provides beneficial reaction conditions, such as uniform flow pattern along the whole reaction capillary, interfacial area with good reproducibility, and intensive water-oil interface renewal. We tested the three-phase flow on an enzyme hydrolysis of soybean oil and compared the reaction conversion with those from unstable two-phase slug flows. We experimentally confirmed that the three-phase slug flow arrangement provides conversions and pressure drops c

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CI - Průmyslová chemie a chemické inženýrství

OECD FORD obor

—

Projekt

<a href="/cs/project/ED2.1.00%2F03.0088" target="_blank" >ED2.1.00/03.0088: Centrum nových technologií a materiálů (CENTEM)</a><br>

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biomicrofluidics

ISSN

1932-1058

e-ISSN

—

Svazek periodika

7

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

13

Strana od-do

"054103-1"-"054103-13"

Kód UT WoS článku

000326877600005

EID výsledku v databázi Scopus

—