The preparation of mono- and multicomponent nanoparticle aggregates with layer-by-layer structure using emulsion templating method in microfluidics

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F22%3A43922737" target="_blank" >RIV/60461373:22340/22:43922737 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68378271:_____/22:00546044

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0009250921006497" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0009250921006497</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ces.2021.117084" target="_blank" >10.1016/j.ces.2021.117084</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The preparation of mono- and multicomponent nanoparticle aggregates with layer-by-layer structure using emulsion templating method in microfluidics

Popis výsledku v původním jazyce

We report on the preparation of multicomponent hollow aggregates by an emulsion templating method adapted to microfluidic format. The method exploits partial miscibility of aqueous colloidal solutions as discrete phase and n-butanol as continuous phase. The aggregates consisted of an inner inorganic shell composed of iron oxide (IO) and gold nanoparticles (Au NPs) covered with polycaprolactone (PCL) NPs. The aggregates of smaller sizes were prepared compared to immiscible phases due to the diffusion-controlled shrinkage of aqueous droplets. The aggregate surface properties were controlled by using different mobilities and affinities of IO, Au, and PCL NPs to the water:n-butanol interface. The biocompatible surface layer enclosing an inorganic shell with a core space for possible cargo loading endowed these constructs with properties appreciated in medicinal applications. A computational fluid dynamics model enabled the prediction of the droplet size and formation frequency together with flow field properties at the point of droplet detachment.

Název v anglickém jazyce

The preparation of mono- and multicomponent nanoparticle aggregates with layer-by-layer structure using emulsion templating method in microfluidics

Popis výsledku anglicky

We report on the preparation of multicomponent hollow aggregates by an emulsion templating method adapted to microfluidic format. The method exploits partial miscibility of aqueous colloidal solutions as discrete phase and n-butanol as continuous phase. The aggregates consisted of an inner inorganic shell composed of iron oxide (IO) and gold nanoparticles (Au NPs) covered with polycaprolactone (PCL) NPs. The aggregates of smaller sizes were prepared compared to immiscible phases due to the diffusion-controlled shrinkage of aqueous droplets. The aggregate surface properties were controlled by using different mobilities and affinities of IO, Au, and PCL NPs to the water:n-butanol interface. The biocompatible surface layer enclosing an inorganic shell with a core space for possible cargo loading endowed these constructs with properties appreciated in medicinal applications. A computational fluid dynamics model enabled the prediction of the droplet size and formation frequency together with flow field properties at the point of droplet detachment.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

21002 - Nano-processes (applications on nano-scale); (biomaterials to be 2.9)

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Chemical Engineering Science

ISSN

0009-2509

e-ISSN

1873-4405

Svazek periodika

247

Číslo periodika v rámci svazku

16 January 2022

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

14

Strana od-do

117084

Kód UT WoS článku

000704364100016

EID výsledku v databázi Scopus

2-s2.0-85115009709