Pituitary adenoma treatment plan quality comparison between linear accelerator volumetric modulated arc therapy and Leksell Gamma Knife (R) radiosurgery
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61383082%3A_____%2F21%3A00001130" target="_blank" >RIV/61383082:_____/21:00001130 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00064203:_____/21:10429910 RIV/68407700:21340/21:00365187 RIV/68407700:21460/21:00365187
Výsledek na webu
<a href="https://www.sciencedirect.com/science/article/abs/pii/S095839472100056X" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S095839472100056X</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.meddos.2021.06.003" target="_blank" >10.1016/j.meddos.2021.06.003</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Pituitary adenoma treatment plan quality comparison between linear accelerator volumetric modulated arc therapy and Leksell Gamma Knife (R) radiosurgery
Popis výsledku v původním jazyce
The aim of this study was to compare radiosurgical treatment plan quality of a linear accelerator with Leksell Gamma Knife (LGK) for pituitary adenoma irradiation. Thirty pituitary adenoma patients were evaluated in this study. Treatment plans were prepared on LGK and stereotactic linear accelerator Varian TrueBeam STx. Volumetric Modulated Arc Therapy (VMAT) plans (21 plans with 2 coplanar arcs and 9 plans with 4 non-coplanar arcs) were calculated for linear accelerator. All the plans were evaluated in terms of conformity, selectivity, gradient index and organ at risk (OAR) sparing. VMAT produced dosimetrically comparable treatment plans to LGK regarding conformity and selectivity (New Conformity Index (NCI): 1.76 +/- 0.65 for 4 arc VMAT, 2.33 +/- 1,16 for 2 arc VMAT and 1.96 +/- 0.71 for LGK; Selectivity Index (SI): 0.63 +/- 0.16 for 4 arc VMAT, 0.51 +/- 0.16 for 2 arc VMAT and 0.58 +/- 0.17 for LGK). Gradient index (GI) was superior for LGK plans (GI: 2.74 +/- 0.20 for LGK and 5.28 +/- 2.29 for 4 arc VMAT). OAR sparing for optics, brainstem, and hypophysis was similar for both modalities while target volume coverage was maintained the same. Finally, treatment time resulted in favor of VMAT plans (in this study VMAT plans were almost 5 times faster than LGK treatment regarding beam on time). According to the results of this study stereotactic linear accelerator with VMAT treatment could be used as a reasonable alternative to LGK for pituitary adenoma radiosurgery but only if the same head fixation method accuracy and target volume delineation are maintained for both modalities. (c) 2021 American Association of Medical Dosimetrists. Published by Elsevier Inc. All rights reserved.
Název v anglickém jazyce
Pituitary adenoma treatment plan quality comparison between linear accelerator volumetric modulated arc therapy and Leksell Gamma Knife (R) radiosurgery
Popis výsledku anglicky
The aim of this study was to compare radiosurgical treatment plan quality of a linear accelerator with Leksell Gamma Knife (LGK) for pituitary adenoma irradiation. Thirty pituitary adenoma patients were evaluated in this study. Treatment plans were prepared on LGK and stereotactic linear accelerator Varian TrueBeam STx. Volumetric Modulated Arc Therapy (VMAT) plans (21 plans with 2 coplanar arcs and 9 plans with 4 non-coplanar arcs) were calculated for linear accelerator. All the plans were evaluated in terms of conformity, selectivity, gradient index and organ at risk (OAR) sparing. VMAT produced dosimetrically comparable treatment plans to LGK regarding conformity and selectivity (New Conformity Index (NCI): 1.76 +/- 0.65 for 4 arc VMAT, 2.33 +/- 1,16 for 2 arc VMAT and 1.96 +/- 0.71 for LGK; Selectivity Index (SI): 0.63 +/- 0.16 for 4 arc VMAT, 0.51 +/- 0.16 for 2 arc VMAT and 0.58 +/- 0.17 for LGK). Gradient index (GI) was superior for LGK plans (GI: 2.74 +/- 0.20 for LGK and 5.28 +/- 2.29 for 4 arc VMAT). OAR sparing for optics, brainstem, and hypophysis was similar for both modalities while target volume coverage was maintained the same. Finally, treatment time resulted in favor of VMAT plans (in this study VMAT plans were almost 5 times faster than LGK treatment regarding beam on time). According to the results of this study stereotactic linear accelerator with VMAT treatment could be used as a reasonable alternative to LGK for pituitary adenoma radiosurgery but only if the same head fixation method accuracy and target volume delineation are maintained for both modalities. (c) 2021 American Association of Medical Dosimetrists. Published by Elsevier Inc. All rights reserved.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
30224 - Radiology, nuclear medicine and medical imaging
Návaznosti výsledku
Projekt
—
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2021
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Medical Dosimetry
ISSN
0958-3947
e-ISSN
—
Svazek periodika
4
Číslo periodika v rámci svazku
440-448
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
1
Strana od-do
9
Kód UT WoS článku
000754202600025
EID výsledku v databázi Scopus
—