Postcovid Guillain-Barré syndrome with severe course – case series two patients including clinical evaluation of smell and examination of olfactory event-related potentials (OERPs)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61383082%3A_____%2F23%3A00001293" target="_blank" >RIV/61383082:_____/23:00001293 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/24:43925386

Výsledek na webu

<a href="https://pubmed.ncbi.nlm.nih.gov/37114704/" target="_blank" >https://pubmed.ncbi.nlm.nih.gov/37114704/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2023.014" target="_blank" >10.5507/bp.2023.014</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Postcovid Guillain-Barré syndrome with severe course – case series two patients including clinical evaluation of smell and examination of olfactory event-related potentials (OERPs)

Popis výsledku v původním jazyce

Introduction. We report a case series two patients of Guillain-Barre syndrome (GBS) associated with previous COVID-19 that both patients survived. GBS is an immune-mediated disease that affects peripheral nerves and can cause life threatening complications. Case Reports. In both cases (53-year-old female and 59-year-old male) with severe GBS with complications, the smell of sense was investigated subjectively using Sniffin' sticks identification tests and objectively using objective olfactometry by the evaluation of olfactory event-related potentials (OERPs). Both patients had good results of the subjective Sniffin' sticks identification test without patholgical findings. Results of objective examination of OERPs: the P2-N1 wave complex was equipotent. No olfactory disturbance could be detected in either case, OERPs were plentiful in both cases. Conclusion. The presentation of a case series two patients of post-covid GBS are an example of one of the many complications of COVID-19 that can cause prolonged recovery. Despite the severe course of GBS and the long recovery time, both patients returned to normal life. An expanded prospective study is planned for the future to investigate post-covid olfactory impairment. The prevalence of GBS associated with COVID-19 is still unknown but it is evident that both mild and severe forms of GBS have been described in patients.

Název v anglickém jazyce

Postcovid Guillain-Barré syndrome with severe course – case series two patients including clinical evaluation of smell and examination of olfactory event-related potentials (OERPs)

Popis výsledku anglicky

Introduction. We report a case series two patients of Guillain-Barre syndrome (GBS) associated with previous COVID-19 that both patients survived. GBS is an immune-mediated disease that affects peripheral nerves and can cause life threatening complications. Case Reports. In both cases (53-year-old female and 59-year-old male) with severe GBS with complications, the smell of sense was investigated subjectively using Sniffin' sticks identification tests and objectively using objective olfactometry by the evaluation of olfactory event-related potentials (OERPs). Both patients had good results of the subjective Sniffin' sticks identification test without patholgical findings. Results of objective examination of OERPs: the P2-N1 wave complex was equipotent. No olfactory disturbance could be detected in either case, OERPs were plentiful in both cases. Conclusion. The presentation of a case series two patients of post-covid GBS are an example of one of the many complications of COVID-19 that can cause prolonged recovery. Despite the severe course of GBS and the long recovery time, both patients returned to normal life. An expanded prospective study is planned for the future to investigate post-covid olfactory impairment. The prevalence of GBS associated with COVID-19 is still unknown but it is evident that both mild and severe forms of GBS have been described in patients.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30206 - Otorhinolaryngology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

BIOMEDICAL PAPERS-OLOMOUC

ISSN

1213-8118

e-ISSN

—

Svazek periodika

167

Číslo periodika v rámci svazku

Apr

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

5

Strana od-do

1-5

Kód UT WoS článku

000983451700001

EID výsledku v databázi Scopus

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