Surgical approaches to head and neck sarcomas – current concepts and perspectives

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61383082%3A_____%2F24%3A00001482" target="_blank" >RIV/61383082:_____/24:00001482 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/24:10486920 RIV/00216208:11120/24:43927679

Výsledek na webu

<a href="https://www.medvik.cz/bmc/view.do?gid=2221542" target="_blank" >https://www.medvik.cz/bmc/view.do?gid=2221542</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.48095/ccorl2024167" target="_blank" >10.48095/ccorl2024167</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Surgical approaches to head and neck sarcomas – current concepts and perspectives

Popis výsledku v původním jazyce

Soft tissue sarcomas represent a unique form of malignancy within the head and neck region, characterized by low incidence. Despite being commonly regarded as rare tumors in adults by numerous authors, sarcomas constitute a subset of malignant diseases associated with poor prognoses across diverse age groups, including children, adolescents, and adults. Recent literature highlights the considerable number of sarcoma cases reported, suggesting that while they may be uncommon, they are not truly rare, with 27,908 cases reported in a seven-year period in Europe among a population of 500 million inhabitants. This emphasizes the importance of recognizing sarcomas as infrequent tumors, rather than being rare. Consequently, it is essential to have up-to-date knowledge and evidence-based recommendations to inform and guide the clinical practice in the management of these heterogeneous types of mesenchymal tumors. Methods: We conducted a literature review about head and neck sarcomas using the Web of Science database. The objective of our review was to identify relevant papers discussing various treatment modalities of sarcomas in the head and neck region. This study analyzed the diagnostic criteria for sarcomas and the therapeutic approach, focusing on the surgical approach for the management of head and neck sarcomas. Discussion: Soft tissue sarcomas of the head and neck are infrequent, with an estimated annual incidence of approximately 5 per 100,000 individuals. Recommendations are based on numerous factors, while directing the attention towards identifying markers implicated as risk factors for sarcomas is crucial. Pathological review coupled with the advancement of molecular techniques is essential for this inquiry. Diagnosis relies heavily on bio psy and histological findings, including immunohistochemistry and the detection of specific tumor markers. Recommended imaging methods include ultrasound, CT, HRCT, MRI, and PET/ CT scans. To achieve precise classification and stratification, we must include a multidisciplinary oncological team constructed of pathologists, oncologists, surgeons, and radiologists. Treatment protocol and planning for head and neck sarcomas take into consideration factors such as size, localization, and bio logical behavior, as described in existing literature. The literature extensively analyzes data connected to fundamental treatment modalities in oncology, including surgery, radiotherapy, and chemotherapy. Radical surgery, ensuring R0 margins, is defi nite in the treatment approach.

Název v anglickém jazyce

Surgical approaches to head and neck sarcomas – current concepts and perspectives

Popis výsledku anglicky

Soft tissue sarcomas represent a unique form of malignancy within the head and neck region, characterized by low incidence. Despite being commonly regarded as rare tumors in adults by numerous authors, sarcomas constitute a subset of malignant diseases associated with poor prognoses across diverse age groups, including children, adolescents, and adults. Recent literature highlights the considerable number of sarcoma cases reported, suggesting that while they may be uncommon, they are not truly rare, with 27,908 cases reported in a seven-year period in Europe among a population of 500 million inhabitants. This emphasizes the importance of recognizing sarcomas as infrequent tumors, rather than being rare. Consequently, it is essential to have up-to-date knowledge and evidence-based recommendations to inform and guide the clinical practice in the management of these heterogeneous types of mesenchymal tumors. Methods: We conducted a literature review about head and neck sarcomas using the Web of Science database. The objective of our review was to identify relevant papers discussing various treatment modalities of sarcomas in the head and neck region. This study analyzed the diagnostic criteria for sarcomas and the therapeutic approach, focusing on the surgical approach for the management of head and neck sarcomas. Discussion: Soft tissue sarcomas of the head and neck are infrequent, with an estimated annual incidence of approximately 5 per 100,000 individuals. Recommendations are based on numerous factors, while directing the attention towards identifying markers implicated as risk factors for sarcomas is crucial. Pathological review coupled with the advancement of molecular techniques is essential for this inquiry. Diagnosis relies heavily on bio psy and histological findings, including immunohistochemistry and the detection of specific tumor markers. Recommended imaging methods include ultrasound, CT, HRCT, MRI, and PET/ CT scans. To achieve precise classification and stratification, we must include a multidisciplinary oncological team constructed of pathologists, oncologists, surgeons, and radiologists. Treatment protocol and planning for head and neck sarcomas take into consideration factors such as size, localization, and bio logical behavior, as described in existing literature. The literature extensively analyzes data connected to fundamental treatment modalities in oncology, including surgery, radiotherapy, and chemotherapy. Radical surgery, ensuring R0 margins, is defi nite in the treatment approach.

Druh

J_ost - Ostatní články v recenzovaných periodicích

CEP obor

—

OECD FORD obor

30206 - Otorhinolaryngology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Otorinolaryngologie a foniatrie

ISSN

1210-7867

e-ISSN

—

Svazek periodika

73

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

9

Strana od-do

167-175

Kód UT WoS článku

—

EID výsledku v databázi Scopus

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