The study of the interaction of human mesenchymal stem cells and monocytes/macrophages with single-walled carbon nanotube films

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F06%3A00078673" target="_blank" >RIV/61388955:_____/06:00078673 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

The study of the interaction of human mesenchymal stem cells and monocytes/macrophages with single-walled carbon nanotube films

Popis výsledku v původním jazyce

The influence of single-walled carbon nanotubes (SWCNT) films on two different human cell types (MSC - mesenchymal stem cells (primary cells) and THP-1- monocytes/macrophages cell line) was investigated. We focused our study on the metabolic activity ofthese cells. The SWCNT were impurity free as it was confirmed by Raman and VIS-NIR spectroscopy. No surfactant has been used to minimize the effect of other agents on the behavior of the cells. The results obtained on SWCNT films were compared to those measured on carbon fibers (CF). The metabolic activity of the investigated cell types cultured on SWCNT film was only slightly reduced (about 20%). On the other hand carbon fibers led to much stronger decrease of the cell metabolic activity (about 40%). The cell types under study reacted in cell-number dependent way. The more cells are present, the less metabolic inhibition is observed.

Název v anglickém jazyce

The study of the interaction of human mesenchymal stem cells and monocytes/macrophages with single-walled carbon nanotube films

Popis výsledku anglicky

The influence of single-walled carbon nanotubes (SWCNT) films on two different human cell types (MSC - mesenchymal stem cells (primary cells) and THP-1- monocytes/macrophages cell line) was investigated. We focused our study on the metabolic activity ofthese cells. The SWCNT were impurity free as it was confirmed by Raman and VIS-NIR spectroscopy. No surfactant has been used to minimize the effect of other agents on the behavior of the cells. The results obtained on SWCNT films were compared to those measured on carbon fibers (CF). The metabolic activity of the investigated cell types cultured on SWCNT film was only slightly reduced (about 20%). On the other hand carbon fibers led to much stronger decrease of the cell metabolic activity (about 40%). The cell types under study reacted in cell-number dependent way. The more cells are present, the less metabolic inhibition is observed.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CG - Elektrochemie

OECD FORD obor

—

Projekt

<a href="/cs/project/IAA4040306" target="_blank" >IAA4040306: Přenos náboje v organizovaných supramolekulárních soustavách fullerenů</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2006

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Physica Status Solidi B-Basic Solid State Physics

ISSN

0370-1972

e-ISSN

—

Svazek periodika

243

Číslo periodika v rámci svazku

13

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

5

Strana od-do

—

Kód UT WoS článku

000242187000115

EID výsledku v databázi Scopus

—