There Is No Simple Model of the Plasma Membrane Organization

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F16%3A00463189" target="_blank" >RIV/61388955:_____/16:00463189 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.3389/fcell.2016.00106" target="_blank" >http://dx.doi.org/10.3389/fcell.2016.00106</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3389/fcell.2016.00106" target="_blank" >10.3389/fcell.2016.00106</a>

Jazyk výsledku

angličtina

Název v původním jazyce

There Is No Simple Model of the Plasma Membrane Organization

Popis výsledku v původním jazyce

Ever since technologies enabled the characterization of eukaryotic plasma membranes, heterogeneities in the distributions of its constituents were observed. Over the years this led to the proposal of various models describing the plasma membrane organization such as lipid shells, picket-and-fences, lipid rafts, or protein islands, as addressed in numerous publications and reviews. Instead of emphasizing on one model we in this review give a brief overview over current models and highlight how current experimental work in one or the other way do not support the existence of a single overarching model. Instead, we highlight the vast variety of membrane properties and components, their influences and impacts. We believe that highlighting such controversial discoveries will stimulate unbiased research on plasma membrane organization and functionality, leading to a better understanding of this essential cellular structure.

Název v anglickém jazyce

There Is No Simple Model of the Plasma Membrane Organization

Popis výsledku anglicky

Ever since technologies enabled the characterization of eukaryotic plasma membranes, heterogeneities in the distributions of its constituents were observed. Over the years this led to the proposal of various models describing the plasma membrane organization such as lipid shells, picket-and-fences, lipid rafts, or protein islands, as addressed in numerous publications and reviews. Instead of emphasizing on one model we in this review give a brief overview over current models and highlight how current experimental work in one or the other way do not support the existence of a single overarching model. Instead, we highlight the vast variety of membrane properties and components, their influences and impacts. We believe that highlighting such controversial discoveries will stimulate unbiased research on plasma membrane organization and functionality, leading to a better understanding of this essential cellular structure.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10403 - Physical chemistry

Projekt

<a href="/cs/project/GA15-06989S" target="_blank" >GA15-06989S: Nanoskopická organizace a funkce koreceptoru CD4 na povrchu T buněk</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Frontiers in cell and developmental biology

ISSN

2296-634X

e-ISSN

—

Svazek periodika

4

Číslo periodika v rámci svazku

SEP 2016

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

17

Strana od-do

106

Kód UT WoS článku

000455229700106

EID výsledku v databázi Scopus

2-s2.0-85018625624