Facile Construction and In Silico Study of Quinoline-Attached Resorcinarene Fluorescent Sensor for the Recognition of Insensitive Munition Compounds

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F18%3A00502543" target="_blank" >RIV/61388955:_____/18:00502543 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1002/slct.201802586" target="_blank" >http://dx.doi.org/10.1002/slct.201802586</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/slct.201802586" target="_blank" >10.1002/slct.201802586</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Facile Construction and In Silico Study of Quinoline-Attached Resorcinarene Fluorescent Sensor for the Recognition of Insensitive Munition Compounds

Popis výsledku v původním jazyce

N-methyl-4-nitroaniline (MNA), an insensitive munition is selectively and sensitively recognized by a new resorcinarene bearing quinoline moiety, i.e, Tetra-Methoxy Resorcinarene Tetra-Quinoline Acetamide (TMRTQA). A simple and efficient spectrofluorimetric technique demonstrates the quenching of the fluorescence intensity of TMRTQA upon addition of MNA within concentration limits of 2 nM to 1 mu M. Binding constant and quantum yield have been determined in this study. Molecular docking studies have been performed to predict the best binding affinity and the possible interactions for the formation of complex between TMRTQA and MNA supporting the 1:1 stoichiometry. Density functional theory calculation also support the excitation wavelength and geometry optimization. MNA being a hazardous environmental pollutant has been successfully detected from the water sample by standard addition method.

Název v anglickém jazyce

Facile Construction and In Silico Study of Quinoline-Attached Resorcinarene Fluorescent Sensor for the Recognition of Insensitive Munition Compounds

Popis výsledku anglicky

N-methyl-4-nitroaniline (MNA), an insensitive munition is selectively and sensitively recognized by a new resorcinarene bearing quinoline moiety, i.e, Tetra-Methoxy Resorcinarene Tetra-Quinoline Acetamide (TMRTQA). A simple and efficient spectrofluorimetric technique demonstrates the quenching of the fluorescence intensity of TMRTQA upon addition of MNA within concentration limits of 2 nM to 1 mu M. Binding constant and quantum yield have been determined in this study. Molecular docking studies have been performed to predict the best binding affinity and the possible interactions for the formation of complex between TMRTQA and MNA supporting the 1:1 stoichiometry. Density functional theory calculation also support the excitation wavelength and geometry optimization. MNA being a hazardous environmental pollutant has been successfully detected from the water sample by standard addition method.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10405 - Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)

Projekt

<a href="/cs/project/GA17-18108S" target="_blank" >GA17-18108S: Nové elektrochemicky aktivní thiacalix[4]areny a jejich oxidovaná analoga jako ligandy a receptory</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

ChemistrySelect

ISSN

2365-6549

e-ISSN

—

Svazek periodika

3

Číslo periodika v rámci svazku

45

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

9

Strana od-do

12951-12959

Kód UT WoS článku

000452260800030

EID výsledku v databázi Scopus

2-s2.0-85057748481