Comparison of mononuclear and dinuclear copper(ii) biomimetic complexes: spectroelectrochemical mechanistic study of their catalytic pathways

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F22%3A00561664" target="_blank" >RIV/61388955:_____/22:00561664 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216275:25310/22:39918877

Výsledek na webu

<a href="https://hdl.handle.net/11104/0334189" target="_blank" >https://hdl.handle.net/11104/0334189</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1039/d2dt01610a" target="_blank" >10.1039/d2dt01610a</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Comparison of mononuclear and dinuclear copper(ii) biomimetic complexes: spectroelectrochemical mechanistic study of their catalytic pathways

Popis výsledku v původním jazyce

Two catecholase-like biomimetic catalysts, namely, two dinuclear copper complexes [Cu-2(L1)(OH)(H2O)(EtOH)][ClO4](2) (C1) and [Cu2Ac2O(L1)ClO4] (C2) with the 2,6-bis(4-methyl piperazin-1-yl-methyl)-4-formyl-phenoxy ligand (L1) together with the mononuclear complex Cu(ClO4)(2)(L2) (C3) containing ligand 1,2-(C5H4N-6-OCH3-2-CH=N)(2)CH2CH2 (L2), were synthesized. Their catalytic pathways were investigated and compared. The evaluation of the catalytic activity of compound C1 (and C2, C3) using the Michaelis-Menten model was represented by values of K-M = 272.93 (223.02, 1616) mu mol L-1 and V-max of 0.981 (1.617, 1.689) mu mol L-1 s(-1). The role of water content in the solvent is also discussed. The dinuclear complexes C1 and C2 were found to be more efficient catalysts than mononuclear complex C3. The mode of catalytic action was characterized via cyclic voltammetry, spectrophotometry, and UV-Vis spectroelectrochemistry. The catalytic mechanism of 3,5-di-tert butyl catechol oxidation in the presence of oxygen was proposed. The reaction circle was proved by the confirmation of the chemical reversibility of complex reduction. The advantage of the in situ spectroelectrochemical measurement enabled to control the reduction of quinone formed by the chemical reaction of catechol with oxygen in solution. At this step, the simultaneous change in the absorption spectrum indicated a change in the copper redox state of the catalyst.

Název v anglickém jazyce

Comparison of mononuclear and dinuclear copper(ii) biomimetic complexes: spectroelectrochemical mechanistic study of their catalytic pathways

Popis výsledku anglicky

Two catecholase-like biomimetic catalysts, namely, two dinuclear copper complexes [Cu-2(L1)(OH)(H2O)(EtOH)][ClO4](2) (C1) and [Cu2Ac2O(L1)ClO4] (C2) with the 2,6-bis(4-methyl piperazin-1-yl-methyl)-4-formyl-phenoxy ligand (L1) together with the mononuclear complex Cu(ClO4)(2)(L2) (C3) containing ligand 1,2-(C5H4N-6-OCH3-2-CH=N)(2)CH2CH2 (L2), were synthesized. Their catalytic pathways were investigated and compared. The evaluation of the catalytic activity of compound C1 (and C2, C3) using the Michaelis-Menten model was represented by values of K-M = 272.93 (223.02, 1616) mu mol L-1 and V-max of 0.981 (1.617, 1.689) mu mol L-1 s(-1). The role of water content in the solvent is also discussed. The dinuclear complexes C1 and C2 were found to be more efficient catalysts than mononuclear complex C3. The mode of catalytic action was characterized via cyclic voltammetry, spectrophotometry, and UV-Vis spectroelectrochemistry. The catalytic mechanism of 3,5-di-tert butyl catechol oxidation in the presence of oxygen was proposed. The reaction circle was proved by the confirmation of the chemical reversibility of complex reduction. The advantage of the in situ spectroelectrochemical measurement enabled to control the reduction of quinone formed by the chemical reaction of catechol with oxygen in solution. At this step, the simultaneous change in the absorption spectrum indicated a change in the copper redox state of the catalyst.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10405 - Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)

Projekt

<a href="/cs/project/GA19-03160S" target="_blank" >GA19-03160S: Elektrochemická studie nových umělých enzymů a jejich role v analýze neurotransmiterů</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Dalton Transactions

ISSN

1477-9226

e-ISSN

1477-9234

Svazek periodika

51

Číslo periodika v rámci svazku

36

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

13

Strana od-do

13703-13715

Kód UT WoS článku

000843687500001

EID výsledku v databázi Scopus

2-s2.0-85137048906