Bilirubin determination at the electrified liquid-liquid interface supported with a 3D printed capillary

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F23%3A00574195" target="_blank" >RIV/61388955:_____/23:00574195 - isvavai.cz</a>

Výsledek na webu

<a href="https://hdl.handle.net/11104/0344543" target="_blank" >https://hdl.handle.net/11104/0344543</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.snb.2023.134360" target="_blank" >10.1016/j.snb.2023.134360</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Bilirubin determination at the electrified liquid-liquid interface supported with a 3D printed capillary

Popis výsledku v původním jazyce

In this work, we have studied the behavior of bilirubin at the electrified liquid-liquid interface using two voltammetric techniques - cyclic and differential pulse voltammetry. The effect of bilirubin concentration as the analyte, and the influence of the aqueous phase pH on the interfacial behavior were investigated. Our focus was to optimize the electroanalytical determination protocol of bilirubin at the electrified liquid-liquid interface with the buffered aqueous phase (physicochemical study) and/or artificial urine formulation (analytical study). In this respect, we have extracted a number of electroanalytical parameters concerning bilirubin covering limits of detection and quantification and sensitivities. To push the optimized protocol towards applicability, we have designed and fabricated a 3D printed polyamide based tube finished with an aperture supporting a soft junction. Liquid-liquid interface placed in a fabricated support was characterized using voltammetry and scanning electron microscopy. With 3D printed platform we have significantly reduced the amount of consumed chemicals (from a few mL to a few tens of µL) and obtained a few times lower limit of determination as compared with the macroscopic apparatus.

Název v anglickém jazyce

Bilirubin determination at the electrified liquid-liquid interface supported with a 3D printed capillary

Popis výsledku anglicky

In this work, we have studied the behavior of bilirubin at the electrified liquid-liquid interface using two voltammetric techniques - cyclic and differential pulse voltammetry. The effect of bilirubin concentration as the analyte, and the influence of the aqueous phase pH on the interfacial behavior were investigated. Our focus was to optimize the electroanalytical determination protocol of bilirubin at the electrified liquid-liquid interface with the buffered aqueous phase (physicochemical study) and/or artificial urine formulation (analytical study). In this respect, we have extracted a number of electroanalytical parameters concerning bilirubin covering limits of detection and quantification and sensitivities. To push the optimized protocol towards applicability, we have designed and fabricated a 3D printed polyamide based tube finished with an aperture supporting a soft junction. Liquid-liquid interface placed in a fabricated support was characterized using voltammetry and scanning electron microscopy. With 3D printed platform we have significantly reduced the amount of consumed chemicals (from a few mL to a few tens of µL) and obtained a few times lower limit of determination as compared with the macroscopic apparatus.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10405 - Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Sensors and Actuators B - Chemical

ISSN

0925-4005

e-ISSN

0925-4005

Svazek periodika

394

Číslo periodika v rámci svazku

NOV 2023

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

13

Strana od-do

134360

Kód UT WoS článku

001131890100001

EID výsledku v databázi Scopus

2-s2.0-85166522819