Electrochemical Surface-Enhanced Raman Spectroscopy of acetaminophen: Adsorption dynamics and charge transfer mechanism

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F25%3A00638249" target="_blank" >RIV/61388955:_____/25:00638249 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/67985882:_____/25:00638249 RIV/60461373:22340/25:43932037

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0927775725017042?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0927775725017042?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.colsurfa.2025.137801" target="_blank" >10.1016/j.colsurfa.2025.137801</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Electrochemical Surface-Enhanced Raman Spectroscopy of acetaminophen: Adsorption dynamics and charge transfer mechanism

Popis výsledku v původním jazyce

Electrochemical Surface-Enhanced Raman Spectroscopy (EC-SERS) enables detailed study of molecular adsorption and charge transfer at metal surfaces. This work investigates acetaminophen (AAP) adsorption on a roughened copper electrode using EC-SERS combined with cyclic voltammetry (CV). CV confirms AAP´s electrochemical stability within1000 to 0 mV, allowing analysis of adsorption without redox interference. AAP rapidly adsorbs within eight CV cycles (similar to 13 min), forming stable surface complexes primarily through amine group interactions. Desorption is slower, indicated by gradual changes in electrochemical current and Raman signal during reverse scans. The highest SERS enhancement occurs at600 mV, where optimal charge transfer and molecular orientation maximize signal intensity. Density functional theory calculations support experimental findings, confirming the formation of metal-molecule ´complexes´ consistent with observed vibrational modes. The study highlights the influence of applied potential on adsorption/desorption dynamics and demonstrates copper's promise as an affordable EC-SERS substrate. Despite lower enhancement compared to noble metals, copper's biocompatibility and surface versatility make it suitable for biomedical and environmental sensing applications. These insights contribute to the advancement of electrochemical sensors based on EC-SERS for pharmaceutical and bioanalytical uses.

Název v anglickém jazyce

Electrochemical Surface-Enhanced Raman Spectroscopy of acetaminophen: Adsorption dynamics and charge transfer mechanism

Popis výsledku anglicky

Electrochemical Surface-Enhanced Raman Spectroscopy (EC-SERS) enables detailed study of molecular adsorption and charge transfer at metal surfaces. This work investigates acetaminophen (AAP) adsorption on a roughened copper electrode using EC-SERS combined with cyclic voltammetry (CV). CV confirms AAP´s electrochemical stability within1000 to 0 mV, allowing analysis of adsorption without redox interference. AAP rapidly adsorbs within eight CV cycles (similar to 13 min), forming stable surface complexes primarily through amine group interactions. Desorption is slower, indicated by gradual changes in electrochemical current and Raman signal during reverse scans. The highest SERS enhancement occurs at600 mV, where optimal charge transfer and molecular orientation maximize signal intensity. Density functional theory calculations support experimental findings, confirming the formation of metal-molecule ´complexes´ consistent with observed vibrational modes. The study highlights the influence of applied potential on adsorption/desorption dynamics and demonstrates copper's promise as an affordable EC-SERS substrate. Despite lower enhancement compared to noble metals, copper's biocompatibility and surface versatility make it suitable for biomedical and environmental sensing applications. These insights contribute to the advancement of electrochemical sensors based on EC-SERS for pharmaceutical and bioanalytical uses.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10403 - Physical chemistry

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Colloids and Surfaces A-Physicochemical and Engineering Aspects

ISSN

0927-7757

e-ISSN

1873-4359

Svazek periodika

726

Číslo periodika v rámci svazku

Part 2

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

9

Strana od-do

137801

Kód UT WoS článku

001542118000005

EID výsledku v databázi Scopus

2-s2.0-105011479992