Cytotoxicity of fluorographene

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F15%3A00455753" target="_blank" >RIV/61388963:_____/15:00455753 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60461373:22310/15:43899730

Výsledek na webu

<a href="http://dx.doi.org/10.1039/c5ra22663e" target="_blank" >http://dx.doi.org/10.1039/c5ra22663e</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1039/c5ra22663e" target="_blank" >10.1039/c5ra22663e</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Cytotoxicity of fluorographene

Popis výsledku v původním jazyce

Fluorinated graphenes (F-G) are gaining popularity in recent years and should they be introduced commercially in the future, these nanomaterials will inevitably be released into the environment through disposal or wearing of the products. In view of this, we attempted to investigate the cytotoxicity of three F-G nanomaterials in this study, with the use of two well-established cell viability assays, to find out their impact on mammalian cells and how their physiochemical properties might affect the extent of their cytotoxicity. Cell viability measurements on A549 cells following 24 h exposure to the F-G revealed that F-G does impart dose-dependent toxicological effects on the cells, and the level of cytotoxicity induced by the nanomaterials differed vastly. It was suggested that the fluorine content, in particular the types of fluorine-containing groups present in the nanomaterial played significant roles in affecting its cytotoxicity. In addition, control experiments which were conduc

Název v anglickém jazyce

Cytotoxicity of fluorographene

Popis výsledku anglicky

Fluorinated graphenes (F-G) are gaining popularity in recent years and should they be introduced commercially in the future, these nanomaterials will inevitably be released into the environment through disposal or wearing of the products. In view of this, we attempted to investigate the cytotoxicity of three F-G nanomaterials in this study, with the use of two well-established cell viability assays, to find out their impact on mammalian cells and how their physiochemical properties might affect the extent of their cytotoxicity. Cell viability measurements on A549 cells following 24 h exposure to the F-G revealed that F-G does impart dose-dependent toxicological effects on the cells, and the level of cytotoxicity induced by the nanomaterials differed vastly. It was suggested that the fluorine content, in particular the types of fluorine-containing groups present in the nanomaterial played significant roles in affecting its cytotoxicity. In addition, control experiments which were conduc

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CC - Organická chemie

OECD FORD obor

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Projekt

<a href="/cs/project/GA15-09001S" target="_blank" >GA15-09001S: Chemické modifikace materiálů na bázi grafenu: Syntéza grafanu a halogengrafenu</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

RSC Advances

ISSN

2046-2069

e-ISSN

—

Svazek periodika

5

Číslo periodika v rámci svazku

129

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

8

Strana od-do

107158-107165

Kód UT WoS článku

000367274300097

EID výsledku v databázi Scopus

2-s2.0-84951773497