Pregnanolone derivatives substituted in 3alpha-position with the cationic group, usage and pharmaceutical preparation involving them

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F18%3A00500216" target="_blank" >RIV/61388963:_____/18:00500216 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/67985823:_____/18:00500216

Výsledek na webu

<a href="https://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=20180418&DB=&locale=en_EP&CC=EP&NR=2675821B1&KC=B1&ND=4#" target="_blank" >https://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=20180418&DB=&locale=en_EP&CC=EP&NR=2675821B1&KC=B1&ND=4#</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Pregnanolone derivatives substituted in 3alpha-position with the cationic group, usage and pharmaceutical preparation involving them

Popis výsledku v původním jazyce

The presented invention applies to pregnanolone derivatives, substituted in 3 alpha-position with the cationic group, of general formula I, the method of the production of these compounds and their utilization for treatment of neuropsychiatric disorders related to imbalance of glutamatergic neurotransmitter system, such as ischemic damage of CNS, neurodegenerative changes and disorders of CNS, affective disorders, depression, post traumatic stress dissorder, and other diseases related to stress, anxiety, schizophrenia, and psychotic disorders, pain, addictions, multiple sclerosis, epilepsy, and gliomas. The object of invention is also the use of compounds of general formula I for production of veterinary and human pharmaceutical preparation for treatment of above mentioned diseases and for production of pharmaceutical preparations containing these compounds.

Název v anglickém jazyce

Pregnanolone derivatives substituted in 3alpha-position with the cationic group, usage and pharmaceutical preparation involving them

Popis výsledku anglicky

The presented invention applies to pregnanolone derivatives, substituted in 3 alpha-position with the cationic group, of general formula I, the method of the production of these compounds and their utilization for treatment of neuropsychiatric disorders related to imbalance of glutamatergic neurotransmitter system, such as ischemic damage of CNS, neurodegenerative changes and disorders of CNS, affective disorders, depression, post traumatic stress dissorder, and other diseases related to stress, anxiety, schizophrenia, and psychotic disorders, pain, addictions, multiple sclerosis, epilepsy, and gliomas. The object of invention is also the use of compounds of general formula I for production of veterinary and human pharmaceutical preparation for treatment of above mentioned diseases and for production of pharmaceutical preparations containing these compounds.

Druh

P - Patent

CEP obor

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OECD FORD obor

10401 - Organic chemistry

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Číslo patentu nebo vzoru

EP2675821

Vydavatel

EPO_1 -

Název vydavatele

European Patent Office

Místo vydání

Munich, The Hague, Berlin, Vienna, Brussels

Stát vydání

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Datum přijetí

18. 4. 2018

Název vlastníka

Ústav organické chemie a biochemie AV ČR, v. v. i. - Fyziologický ústav AV ČR, v. v. i

Způsob využití

A - Výsledek využívá pouze poskytovatel

Druh možnosti využití

A - K využití výsledku jiným subjektem je vždy nutné nabytí licence