Chiral detection by induced surface-enhanced Raman optical activity

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F21%3A00543207" target="_blank" >RIV/61388963:_____/21:00543207 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60461373:22340/21:43922115 RIV/61989592:15310/21:73607476

Výsledek na webu

<a href="https://doi.org/10.1039/D1CC01504D" target="_blank" >https://doi.org/10.1039/D1CC01504D</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1039/d1cc01504d" target="_blank" >10.1039/d1cc01504d</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Chiral detection by induced surface-enhanced Raman optical activity

Popis výsledku v původním jazyce

Combination of optical activity with surface-enhanced Raman scattering has been a dream of physical chemists for a long time. We report a measurement protocol based on silver colloids and aromatic linkers where chiral acids could be detected in concentrations of about 10−5 M. We explain the mechanism by binding and self-assembly of the linkers into chiral aggregates on the silver surface. Following the “sergeants-and-soldiers” principle, the chirality is determined by the relatively minor acidic component. Such detection of biologically relevant molecules may be useful when other methods, such as electronic circular dichroism, are not sensitive enough. In the future, variations of the chemical structure of the linker or other conditions are needed to provide a more specific signal allowing one to better discriminate among the optically active molecules.

Název v anglickém jazyce

Chiral detection by induced surface-enhanced Raman optical activity

Popis výsledku anglicky

Combination of optical activity with surface-enhanced Raman scattering has been a dream of physical chemists for a long time. We report a measurement protocol based on silver colloids and aromatic linkers where chiral acids could be detected in concentrations of about 10−5 M. We explain the mechanism by binding and self-assembly of the linkers into chiral aggregates on the silver surface. Following the “sergeants-and-soldiers” principle, the chirality is determined by the relatively minor acidic component. Such detection of biologically relevant molecules may be useful when other methods, such as electronic circular dichroism, are not sensitive enough. In the future, variations of the chemical structure of the linker or other conditions are needed to provide a more specific signal allowing one to better discriminate among the optically active molecules.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10403 - Physical chemistry

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Chemical Communications

ISSN

1359-7345

e-ISSN

1364-548X

Svazek periodika

57

Číslo periodika v rámci svazku

52

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

4

Strana od-do

6388-6391

Kód UT WoS článku

000657663200001

EID výsledku v databázi Scopus

2-s2.0-85108877040