Software and Computational Tools for LC-MS-Based Epilipidomics: Challenges and Solutions

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F23%3A00567693" target="_blank" >RIV/61388963:_____/23:00567693 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1021/acs.analchem.2c04406" target="_blank" >https://doi.org/10.1021/acs.analchem.2c04406</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1021/acs.analchem.2c04406" target="_blank" >10.1021/acs.analchem.2c04406</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Software and Computational Tools for LC-MS-Based Epilipidomics: Challenges and Solutions

Popis výsledku v původním jazyce

Lipids play a crucial role in cellular structure and functions, including cell signaling, membrane plasticity, and trafficking. Alterations of the lipid composition in cells, tissues, or organelles have been associated with a large number of diseases, including inflammation, cancer, and degenerative or metabolic disorders. Within biological systems, lipids can undergo a range of enzymatic and nonenzymatic reactions (e.g., oxidation, nitration, sulfation, and halogenation) that introduce structural modifications and/or new functional groups to the native molecule. The resulting modified lipid species, generally referred to as “epilipids”, are known to be heavily involved in the regulation of physiological and pathological conditions.

Název v anglickém jazyce

Software and Computational Tools for LC-MS-Based Epilipidomics: Challenges and Solutions

Popis výsledku anglicky

Lipids play a crucial role in cellular structure and functions, including cell signaling, membrane plasticity, and trafficking. Alterations of the lipid composition in cells, tissues, or organelles have been associated with a large number of diseases, including inflammation, cancer, and degenerative or metabolic disorders. Within biological systems, lipids can undergo a range of enzymatic and nonenzymatic reactions (e.g., oxidation, nitration, sulfation, and halogenation) that introduce structural modifications and/or new functional groups to the native molecule. The resulting modified lipid species, generally referred to as “epilipids”, are known to be heavily involved in the regulation of physiological and pathological conditions.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

<a href="/cs/project/GM21-11563M" target="_blank" >GM21-11563M: Mapování chemodiverzity pepřovníkovitých rostlin pomocí nové generace platformy MZmine</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Analytical Chemistry

ISSN

0003-2700

e-ISSN

1520-6882

Svazek periodika

95

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

17

Strana od-do

287-303

Kód UT WoS článku

000916680900001

EID výsledku v databázi Scopus

2-s2.0-85146389789