Structural Characterization of Lipids Using Advanced Mass Spectrometry Approaches

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F23%3A00570588" target="_blank" >RIV/61388963:_____/23:00570588 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1002/9783527836512.ch7" target="_blank" >https://doi.org/10.1002/9783527836512.ch7</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/9783527836512.ch7" target="_blank" >10.1002/9783527836512.ch7</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Structural Characterization of Lipids Using Advanced Mass Spectrometry Approaches

Popis výsledku v původním jazyce

Over the years, mass spectrometry has emerged as the principal method for identifying lipids in biological samples. In lipidomics, mass spectrometry analyzes hundreds of molecular species to understand cellular processes better. Since biological function depends on structure, it is essential to characterize lipid molecules comprehensively. Technological improvements in mass spectrometry and research that brought new methods have significantly advanced the possibilities of structural analysis of lipids. Most lipids contain aliphatic chains, which cause the structural variability of molecular species within a lipid class. The lipid chains can be straight or branched, saturated or unsaturated, and modified by various functional groups. Common mass spectrometry methods usually do not reveal much about the structure of the chains. The derivatization of lipids and/or advanced ion activation techniques are used to learn more. This chapter reviews current approaches for characterizing acyl chains structure using atmospheric-pressure ionization mass spectrometry.

Název v anglickém jazyce

Structural Characterization of Lipids Using Advanced Mass Spectrometry Approaches

Popis výsledku anglicky

Over the years, mass spectrometry has emerged as the principal method for identifying lipids in biological samples. In lipidomics, mass spectrometry analyzes hundreds of molecular species to understand cellular processes better. Since biological function depends on structure, it is essential to characterize lipid molecules comprehensively. Technological improvements in mass spectrometry and research that brought new methods have significantly advanced the possibilities of structural analysis of lipids. Most lipids contain aliphatic chains, which cause the structural variability of molecular species within a lipid class. The lipid chains can be straight or branched, saturated or unsaturated, and modified by various functional groups. Common mass spectrometry methods usually do not reveal much about the structure of the chains. The derivatization of lipids and/or advanced ion activation techniques are used to learn more. This chapter reviews current approaches for characterizing acyl chains structure using atmospheric-pressure ionization mass spectrometry.

Druh

C - Kapitola v odborné knize

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Mass Spectrometry for Lipidomics: Methods and Applications

ISBN

978-3-527-35221-0

Počet stran výsledku

44

Strana od-do

183-226

Počet stran knihy

752

Název nakladatele

Wiley-VCH

Místo vydání

Weinheim

Kód UT WoS kapitoly

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