Detection of viable SARS-CoV-2 on the hands of hospitalized children with COVID-19

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F23%3A00575183" target="_blank" >RIV/61388963:_____/23:00575183 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11310/23:10470832

Výsledek na webu

<a href="https://doi.org/10.1016/j.cmi.2023.06.012" target="_blank" >https://doi.org/10.1016/j.cmi.2023.06.012</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.cmi.2023.06.012" target="_blank" >10.1016/j.cmi.2023.06.012</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Detection of viable SARS-CoV-2 on the hands of hospitalized children with COVID-19

Popis výsledku v původním jazyce

Potential routes of SARS-CoV-2 transmission have been a matter of debate since the early phase of the current COVID-19 pandemic. Similar to other respiratory viruses, airborne droplets exhaled by an infected individual and inhaled by another susceptible person were identified as the dominant route of transmission. However, indirect routes of transmitting SARS-CoV-2 are still under investigation. Transmission by indirect contact has been reported for other respiratory viruses, and therefore, it was intuitive to place great emphasis on the importance of appropriate hand disinfection during the COVID-19 pandemic. Yet, data providing firm evidence for the presence and quantity of potentially infectious virus carried on the hands of patients infected with SARS-CoV-2 remained scarce. We provide here the first experimental evidence supporting the notion that hand-borne SARS-CoV-2 from infected patients can display infectious potential, thus confirming the possibility of virus transmission via an indirect route. Our observation emphasizes the role of frequent hand hygiene as a preventive measure and supports established recommendations - particularly during active infection. The observations presented should serve as a basis for further assessment of the potential role of SARS-CoV-2 transmission via virus-contaminated hands, particularly in epidemiologically critical settings, to facilitate the implementation of optimized strategies for preventing uncontrolled spread of the infection in the current pandemic and any future outbreaks.

Název v anglickém jazyce

Detection of viable SARS-CoV-2 on the hands of hospitalized children with COVID-19

Popis výsledku anglicky

Potential routes of SARS-CoV-2 transmission have been a matter of debate since the early phase of the current COVID-19 pandemic. Similar to other respiratory viruses, airborne droplets exhaled by an infected individual and inhaled by another susceptible person were identified as the dominant route of transmission. However, indirect routes of transmitting SARS-CoV-2 are still under investigation. Transmission by indirect contact has been reported for other respiratory viruses, and therefore, it was intuitive to place great emphasis on the importance of appropriate hand disinfection during the COVID-19 pandemic. Yet, data providing firm evidence for the presence and quantity of potentially infectious virus carried on the hands of patients infected with SARS-CoV-2 remained scarce. We provide here the first experimental evidence supporting the notion that hand-borne SARS-CoV-2 from infected patients can display infectious potential, thus confirming the possibility of virus transmission via an indirect route. Our observation emphasizes the role of frequent hand hygiene as a preventive measure and supports established recommendations - particularly during active infection. The observations presented should serve as a basis for further assessment of the potential role of SARS-CoV-2 transmission via virus-contaminated hands, particularly in epidemiologically critical settings, to facilitate the implementation of optimized strategies for preventing uncontrolled spread of the infection in the current pandemic and any future outbreaks.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10607 - Virology

Projekt

<a href="/cs/project/LX22NPO5103" target="_blank" >LX22NPO5103: Národní institut virologie a bakteriologie</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Clinical Microbiology and Infection

ISSN

1198-743X

e-ISSN

1469-0691

Svazek periodika

29

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

CA - Kanada

Počet stran výsledku

3

Strana od-do

1211-1213

Kód UT WoS článku

001065276600001

EID výsledku v databázi Scopus

2-s2.0-85168382717