If the 5’ cap fits (wear it) – Non-canonical RNA capping

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F24%3A00587708" target="_blank" >RIV/61388963:_____/24:00587708 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11310/24:10487639

Výsledek na webu

<a href="https://doi.org/10.1080/15476286.2024.2372138" target="_blank" >https://doi.org/10.1080/15476286.2024.2372138</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/15476286.2024.2372138" target="_blank" >10.1080/15476286.2024.2372138</a>

Jazyk výsledku

angličtina

Název v původním jazyce

If the 5’ cap fits (wear it) – Non-canonical RNA capping

Popis výsledku v původním jazyce

RNA capping is a prominent RNA modification that influences RNA stability, metabolism, and function.While it was long limited to the study of the most abundant eukaryotic canonical m7G cap, the fieldrecently went through a large paradigm shift with the discovery of non-canonical RNA capping inbacteria and ultimately all domains of life. The repertoire of non-canonical caps has expanded toencompass metabolite caps, including NAD, FAD, CoA, UDP-Glucose, and ADP-ribose, alongside alar-mone dinucleoside polyphosphate caps, and methylated phosphate cap-like structures. This reviewoffers an introduction into the field, presenting a summary of the current knowledge about non-canonical RNA caps. We highlight the often still enigmatic biological roles of the caps together withtheir processing enzymes, focusing on the most recent discoveries. Furthermore, we present themethods used for the detection and analysis of these non-canonical RNA caps and thus provide anintroduction into this dynamic new field.

Název v anglickém jazyce

If the 5’ cap fits (wear it) – Non-canonical RNA capping

Popis výsledku anglicky

RNA capping is a prominent RNA modification that influences RNA stability, metabolism, and function.While it was long limited to the study of the most abundant eukaryotic canonical m7G cap, the fieldrecently went through a large paradigm shift with the discovery of non-canonical RNA capping inbacteria and ultimately all domains of life. The repertoire of non-canonical caps has expanded toencompass metabolite caps, including NAD, FAD, CoA, UDP-Glucose, and ADP-ribose, alongside alar-mone dinucleoside polyphosphate caps, and methylated phosphate cap-like structures. This reviewoffers an introduction into the field, presenting a summary of the current knowledge about non-canonical RNA caps. We highlight the often still enigmatic biological roles of the caps together withtheir processing enzymes, focusing on the most recent discoveries. Furthermore, we present themethods used for the detection and analysis of these non-canonical RNA caps and thus provide anintroduction into this dynamic new field.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10608 - Biochemistry and molecular biology

Projekt

<a href="/cs/project/EH22_008%2F0004575" target="_blank" >EH22_008/0004575: RNA pro terapii</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

RNA biology

ISSN

1547-6286

e-ISSN

1555-8584

Svazek periodika

21

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

13

Strana od-do

1-13

Kód UT WoS článku

001271047600001

EID výsledku v databázi Scopus

2-s2.0-85198659024