Chirality Revealed by Raman Optical Activity: Principles, Applications, Recent Developments and Future Prospects

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F24%3A00617473" target="_blank" >RIV/61388963:_____/24:00617473 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60461373:22340/24:43929707

Výsledek na webu

<a href="https://doi.org/10.1007/978-981-97-1703-3_7" target="_blank" >https://doi.org/10.1007/978-981-97-1703-3_7</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-981-97-1703-3_7" target="_blank" >10.1007/978-981-97-1703-3_7</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Chirality Revealed by Raman Optical Activity: Principles, Applications, Recent Developments and Future Prospects

Popis výsledku v původním jazyce

Chirality is a fundamental property of molecules, particularly important in biological systems. The ability to distinguish between enantiomers is crucial in many fields. Raman optical activity (ROA) is a powerful analytical technique that measures the small intensity difference in Raman scattering of right- and left-circularly polarized light by chiral molecules. Due to their sensitivity to stereochemistry, ROA spectra can provide an ample amount of information on both structure and conformational behavior of chiral molecules. Here we present the theoretical background to the subject and an overview of different forms of ROA measurement, including resonance ROA (RROA) and surface-enhanced ROA (SEROA). We also discuss the application of ROA spectroscopy to a variety of molecules, emphasizing the extent of structural information that can be gathered. Although ROA is still a specialized technique, recent advances have led to several new applications and developments. We show several results to illustrate how ROA is opening new opportunities in analytical chemistry. Finally, we discuss recent advances in ROA instrumentation and its advantages and limitations compared to other chiral spectroscopic techniques, such as electronic and vibrational circular dichroism. Hopefully, this chapter provides a comprehensive list of the fundamentals, applications, advancements, and future potential of ROA as a powerful analytical technique for exploring and studying chirality in molecules.

Název v anglickém jazyce

Chirality Revealed by Raman Optical Activity: Principles, Applications, Recent Developments and Future Prospects

Popis výsledku anglicky

Chirality is a fundamental property of molecules, particularly important in biological systems. The ability to distinguish between enantiomers is crucial in many fields. Raman optical activity (ROA) is a powerful analytical technique that measures the small intensity difference in Raman scattering of right- and left-circularly polarized light by chiral molecules. Due to their sensitivity to stereochemistry, ROA spectra can provide an ample amount of information on both structure and conformational behavior of chiral molecules. Here we present the theoretical background to the subject and an overview of different forms of ROA measurement, including resonance ROA (RROA) and surface-enhanced ROA (SEROA). We also discuss the application of ROA spectroscopy to a variety of molecules, emphasizing the extent of structural information that can be gathered. Although ROA is still a specialized technique, recent advances have led to several new applications and developments. We show several results to illustrate how ROA is opening new opportunities in analytical chemistry. Finally, we discuss recent advances in ROA instrumentation and its advantages and limitations compared to other chiral spectroscopic techniques, such as electronic and vibrational circular dichroism. Hopefully, this chapter provides a comprehensive list of the fundamentals, applications, advancements, and future potential of ROA as a powerful analytical technique for exploring and studying chirality in molecules.

Druh

C - Kapitola v odborné knize

CEP obor

—

OECD FORD obor

10403 - Physical chemistry

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Raman Spectroscopy: Advances and Applications

ISBN

978-981-97-1702-6

Počet stran výsledku

22

Strana od-do

145-166

Počet stran knihy

375

Název nakladatele

Springer

Místo vydání

Singapore

Kód UT WoS kapitoly

—