LC MALDI-TOF MS/MS a LC ESI FTMS analýzy HLA-B27 asociovaných peptidů izolovaných z buněk periferní krve

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F08%3A00312354" target="_blank" >RIV/61388971:_____/08:00312354 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68378050:_____/08:00312354 RIV/00023001:_____/08:00001659

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

LC MALDI-TOF MS/MS and LC ESI FTMS analyses of HLA-B27 associated peptides isolated from peripheral blood cells

Popis výsledku v původním jazyce

Peptides eluted from peripheral blood cells of HLA-B 2705 healthy donor were analyzed by LC MALDI MS/MS and LC ESI FTMS techniques. The sequences of 92 peptide ligands identified from one healthy blood donor by LC MALDI-TOF MS/MS were compared with thosepreviously published. It was found that 18 sequences confirmed within 1 ppm mass error by LC ESI FTMS were already described and 3 of them matched with those previously reported from HLA-B 2705 splenocytes. Another 38 sequences validated within the samemass error were not found in SYFPEITHI database and are identified here for the first time. Finally, 36 sequences (5 sequences already published in SYFPEITHI database) were evaluated by LC MALDI-TOF MS/MS but no matches in the list of monoisotopic masses obtained from LC ESI FTMS were found

Název v anglickém jazyce

LC MALDI-TOF MS/MS and LC ESI FTMS analyses of HLA-B27 associated peptides isolated from peripheral blood cells

Popis výsledku anglicky

Peptides eluted from peripheral blood cells of HLA-B 2705 healthy donor were analyzed by LC MALDI MS/MS and LC ESI FTMS techniques. The sequences of 92 peptide ligands identified from one healthy blood donor by LC MALDI-TOF MS/MS were compared with thosepreviously published. It was found that 18 sequences confirmed within 1 ppm mass error by LC ESI FTMS were already described and 3 of them matched with those previously reported from HLA-B 2705 splenocytes. Another 38 sequences validated within the samemass error were not found in SYFPEITHI database and are identified here for the first time. Finally, 36 sequences (5 sequences already published in SYFPEITHI database) were evaluated by LC MALDI-TOF MS/MS but no matches in the list of monoisotopic masses obtained from LC ESI FTMS were found

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EE - Mikrobiologie, virologie

OECD FORD obor

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Projekt

<a href="/cs/project/1A8631" target="_blank" >1A8631: Sequence peptidů eluovaných z HLA-B27 molekul u zdravých a nemocných jedinců</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2008

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Immunology Letters

ISSN

0165-2478

e-ISSN

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Svazek periodika

116

Číslo periodika v rámci svazku

-

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

7

Strana od-do

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Kód UT WoS článku

000262515800018

EID výsledku v databázi Scopus

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