Fungal Metabolites for Microorganism Classification by Mass Spectrometry

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F11%3A00374062" target="_blank" >RIV/61388971:_____/11:00374062 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1021/bk-2011-1065" target="_blank" >http://dx.doi.org/10.1021/bk-2011-1065</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1021/bk-2011-1065" target="_blank" >10.1021/bk-2011-1065</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Fungal Metabolites for Microorganism Classification by Mass Spectrometry

Popis výsledku v původním jazyce

The current molecular, serological and emphasized mass spectral approaches used in fungal diagnostics are evaluated. An overview of low-molecular weight metabolites that have been used in medical mycology during either in vitro or in vivo experiments ispresented. Fungal spores are suggested as a viable source of fungal biomarkers, as conidia inhalation is an important entrance gateway to host infection. In addition to MALDI (Matrix Assisted Laser Desorption/Ionization) typing, an alternative diagnosticmethod based on the knowledge of specific nonribosomal and other fungal metabolite structures is suggested. This approach can be used in fungal mixture analysis and represents a similar benefit to what we have learned from proteomics: going from peptidemapping to peptide sequencing could give better identification rates

Název v anglickém jazyce

Fungal Metabolites for Microorganism Classification by Mass Spectrometry

Popis výsledku anglicky

The current molecular, serological and emphasized mass spectral approaches used in fungal diagnostics are evaluated. An overview of low-molecular weight metabolites that have been used in medical mycology during either in vitro or in vivo experiments ispresented. Fungal spores are suggested as a viable source of fungal biomarkers, as conidia inhalation is an important entrance gateway to host infection. In addition to MALDI (Matrix Assisted Laser Desorption/Ionization) typing, an alternative diagnosticmethod based on the knowledge of specific nonribosomal and other fungal metabolite structures is suggested. This approach can be used in fungal mixture analysis and represents a similar benefit to what we have learned from proteomics: going from peptidemapping to peptide sequencing could give better identification rates

Druh

C - Kapitola v odborné knize

CEP obor

EE - Mikrobiologie, virologie

OECD FORD obor

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Projekt

<a href="/cs/project/LC07017" target="_blank" >LC07017: Centrum nádorové proteomiky</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Rapid Characterization of Microorganisms by Mass Spectrometry

ISBN

978-0-8412-2612-8

Počet stran výsledku

10

Strana od-do

51-60

Počet stran knihy

237

Název nakladatele

American Chemical Society

Místo vydání

Washington DC

Kód UT WoS kapitoly

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