Selective targeting of melanoma by PEG-masked protein-based multifunctional nanoparticles

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F12%3A00379093" target="_blank" >RIV/61388971:_____/12:00379093 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.2147/IJN.S28242" target="_blank" >http://dx.doi.org/10.2147/IJN.S28242</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2147/IJN.S28242" target="_blank" >10.2147/IJN.S28242</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Selective targeting of melanoma by PEG-masked protein-based multifunctional nanoparticles

Popis výsledku v původním jazyce

Background: Nanoparticle-based systems are promising for the development of imaging and therapeutic agents. The main advantage of nanoparticles over traditional systems lies in the possibility of loading multiple functionalities onto a single molecule, which are useful for therapeutic and/or diagnostic purposes. These functionalities include targeting moieties which are able to recognize receptors overexpressed by specific cells and tissues. However, targeted delivery of nanoparticles requires an accurate system design. We present here a rationally designed, genetically engineered, and chemically modified protein-based nanoplatform for cell/tissue-specific targeting

Název v anglickém jazyce

Selective targeting of melanoma by PEG-masked protein-based multifunctional nanoparticles

Popis výsledku anglicky

Background: Nanoparticle-based systems are promising for the development of imaging and therapeutic agents. The main advantage of nanoparticles over traditional systems lies in the possibility of loading multiple functionalities onto a single molecule, which are useful for therapeutic and/or diagnostic purposes. These functionalities include targeting moieties which are able to recognize receptors overexpressed by specific cells and tissues. However, targeted delivery of nanoparticles requires an accurate system design. We present here a rationally designed, genetically engineered, and chemically modified protein-based nanoplatform for cell/tissue-specific targeting

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EC - Imunologie

OECD FORD obor

—

Projekt

—

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Nanomedicine

ISSN

1178-2013

e-ISSN

—

Svazek periodika

7

Číslo periodika v rámci svazku

2012

Stát vydavatele periodika

NZ - Nový Zéland

Počet stran výsledku

11

Strana od-do

1489-1509

Kód UT WoS článku

000302728400001

EID výsledku v databázi Scopus

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