Two faces of microbiota in inflammatory and autoimmune diseases: triggers and drugs

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F13%3A00399835" target="_blank" >RIV/61388971:_____/13:00399835 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1111/apm.12007" target="_blank" >http://dx.doi.org/10.1111/apm.12007</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/apm.12007" target="_blank" >10.1111/apm.12007</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Two faces of microbiota in inflammatory and autoimmune diseases: triggers and drugs

Popis výsledku v původním jazyce

The prevalence of chronic autoimmune and inflammatory diseases, such as inflammatory bowel disease, allergies, or rheumatic diseases, is steadily increasing in developed countries. This increase is probably accelerated by environmental factors, such as decrease in infectious burden or changes in food processing. These lifestyle changes then strongly influence the strongest stimulus for the immune system commensal microbiota. Despite the differences in the affected organ, the immune-mediated diseases have one or more factors in common microbe either as a trigger or as a protector, mucosal barrier dysfunction, and dysregulation of the immune system. The core questions, which microbes are involved and how these diseases can be cured or even prevented still remain unsolved. Powered by the recent progress in technology, by new insights into the function of immune system, by advances in microbiome research, and extended use of gnotobiological techniques, these mechanisms are now being unrave

Název v anglickém jazyce

Two faces of microbiota in inflammatory and autoimmune diseases: triggers and drugs

Popis výsledku anglicky

The prevalence of chronic autoimmune and inflammatory diseases, such as inflammatory bowel disease, allergies, or rheumatic diseases, is steadily increasing in developed countries. This increase is probably accelerated by environmental factors, such as decrease in infectious burden or changes in food processing. These lifestyle changes then strongly influence the strongest stimulus for the immune system commensal microbiota. Despite the differences in the affected organ, the immune-mediated diseases have one or more factors in common microbe either as a trigger or as a protector, mucosal barrier dysfunction, and dysregulation of the immune system. The core questions, which microbes are involved and how these diseases can be cured or even prevented still remain unsolved. Powered by the recent progress in technology, by new insights into the function of immune system, by advances in microbiome research, and extended use of gnotobiological techniques, these mechanisms are now being unrave

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EC - Imunologie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta Pathologica Microbiologica et Immunologica Scandinavica

ISSN

0903-4641

e-ISSN

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Svazek periodika

121

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

DK - Dánské království

Počet stran výsledku

19

Strana od-do

403-421

Kód UT WoS článku

000318239800003

EID výsledku v databázi Scopus

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