Fungal Keratitis Caused by Colletotrichum dematium: Case Study and Review

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F19%3A00517770" target="_blank" >RIV/61388971:_____/19:00517770 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11150/19:10399948 RIV/00216208:11310/19:10399948 RIV/00179906:_____/19:10399948

Výsledek na webu

<a href="https://link.springer.com/article/10.1007%2Fs11046-019-00335-w" target="_blank" >https://link.springer.com/article/10.1007%2Fs11046-019-00335-w</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11046-019-00335-w" target="_blank" >10.1007/s11046-019-00335-w</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Fungal Keratitis Caused by Colletotrichum dematium: Case Study and Review

Popis výsledku v původním jazyce

Colletotrichum species are known as important pathogens of plants with an impact on crop production. Some of these species are also known as a cause of rare ophthalmic infections in humans. A case of keratitis caused by Colletotrichum dematium after corneal trauma in a 56-year-old woman is presented. Infection was diagnosed based on positive microscopy and culture. The fungal isolate was identified by morphological characteristics and DNA sequencing of the ITS rDNA region, -tubulin (tub2) and glyceraldehyde-3-phosphate dehydrogenase (gapdh) genes. The patient responded well to topical therapy with amphotericin B combined with intravenous amphotericin B but improvement was associated with the corneal collagen cross-linking. The review of the literature revealed another 13 cases of C. dematium keratitis, all but one patient having at least one keratitis risk factor in their history. Almost all patients (n=12) were treated with topical polyene antibiotics (natamycin or amphotericin B), improvement and cure were achieved in eight of them.

Název v anglickém jazyce

Fungal Keratitis Caused by Colletotrichum dematium: Case Study and Review

Popis výsledku anglicky

Colletotrichum species are known as important pathogens of plants with an impact on crop production. Some of these species are also known as a cause of rare ophthalmic infections in humans. A case of keratitis caused by Colletotrichum dematium after corneal trauma in a 56-year-old woman is presented. Infection was diagnosed based on positive microscopy and culture. The fungal isolate was identified by morphological characteristics and DNA sequencing of the ITS rDNA region, -tubulin (tub2) and glyceraldehyde-3-phosphate dehydrogenase (gapdh) genes. The patient responded well to topical therapy with amphotericin B combined with intravenous amphotericin B but improvement was associated with the corneal collagen cross-linking. The review of the literature revealed another 13 cases of C. dematium keratitis, all but one patient having at least one keratitis risk factor in their history. Almost all patients (n=12) were treated with topical polyene antibiotics (natamycin or amphotericin B), improvement and cure were achieved in eight of them.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10606 - Microbiology

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Mycopathologia

ISSN

0301-486X

e-ISSN

—

Svazek periodika

184

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

13

Strana od-do

441-453

Kód UT WoS článku

000473079900009

EID výsledku v databázi Scopus

2-s2.0-85064233821