Improving microalgae for biotechnology From genetics to synthetic biology Moving forward but not there yet

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F22%3A00559848" target="_blank" >RIV/61388971:_____/22:00559848 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60076658:12310/22:43905067

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0734975021001919?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0734975021001919?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.biotechadv.2021.107885" target="_blank" >10.1016/j.biotechadv.2021.107885</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Improving microalgae for biotechnology From genetics to synthetic biology Moving forward but not there yet

Popis výsledku v původním jazyce

Microalgae are a diverse group of photosynthetic organisms that can be exploited for the production of different compounds, ranging from crude biomass and biofuels to high value-added biochemicals and synthetic proteins. Traditionally, algal biotechnology relies on bioprospecting to identify new highly productive strains and more recently, on forward genetics to further enhance productivity. However, it has become clear that further improvements in algal productivity for biotechnology is impossible without combining traditional tools with the arising molecular genetics toolkit. We review recent advantages in developing high throughput screening methods, preparing genome-wide mutant libraries, and establishing genome editing techniques. We discuss how algae can be improved in terms of photosynthetic efficiency, biofuel and high value-added compound production. Finally, we critically evaluate developments over recent years and explore future potential in the field.

Název v anglickém jazyce

Improving microalgae for biotechnology From genetics to synthetic biology Moving forward but not there yet

Popis výsledku anglicky

Microalgae are a diverse group of photosynthetic organisms that can be exploited for the production of different compounds, ranging from crude biomass and biofuels to high value-added biochemicals and synthetic proteins. Traditionally, algal biotechnology relies on bioprospecting to identify new highly productive strains and more recently, on forward genetics to further enhance productivity. However, it has become clear that further improvements in algal productivity for biotechnology is impossible without combining traditional tools with the arising molecular genetics toolkit. We review recent advantages in developing high throughput screening methods, preparing genome-wide mutant libraries, and establishing genome editing techniques. We discuss how algae can be improved in terms of photosynthetic efficiency, biofuel and high value-added compound production. Finally, we critically evaluate developments over recent years and explore future potential in the field.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10606 - Microbiology

Projekt

<a href="/cs/project/GA19-12607S" target="_blank" >GA19-12607S: Růst a buněčný cyklus – regulace vstupu do buněčného cyklu a výstupu z něj</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biotechnology Advances

ISSN

0734-9750

e-ISSN

1873-1899

Svazek periodika

58

Číslo periodika v rámci svazku

SEP2022

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

24

Strana od-do

107885

Kód UT WoS článku

000830105100001

EID výsledku v databázi Scopus

2-s2.0-85121337817