Relationship between Functional Capacity and Medication Adherence in Heart Failure

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F23%3A00582513" target="_blank" >RIV/61388971:_____/23:00582513 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61988987:17110/23:A2402NGM RIV/61989592:15110/23:73621172 RIV/00098892:_____/23:10158523 RIV/00843989:_____/23:E0110646

Výsledek na webu

<a href="https://e-coretvasa.cz/artkey/cor-202390-0003_relationship-between-functional-capacity-and-medication-adherence-in-heart-failure.php" target="_blank" >https://e-coretvasa.cz/artkey/cor-202390-0003_relationship-between-functional-capacity-and-medication-adherence-in-heart-failure.php</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.33678/cor.2023.064" target="_blank" >10.33678/cor.2023.064</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Relationship between Functional Capacity and Medication Adherence in Heart Failure

Popis výsledku v původním jazyce

This study investigated the relationship between the subjective New York Heart Association (NYHA) class and objective exercise capacity (VO2peak) in patients with heart failure and whether it is influenced by medication adherence. Methods: Data from 170 heart failure patients in the Level-CHF register were analysed, and adherence was assessed by serum drug level testing. Objective exercise capacity was assessed by cardiopulmonary exercise testing using a bicycle ergometer. Results: Objective VO2peak frequently exceeded the subjective NYHA class with 46% concordance, especially at the extreme ends of the spectrum. Minor differences in subjective NYHA class in relation to medication adherence were noted, but no substantial disparity was observed. Conclusion: These findings highlight the discrepancies between subjective and objective assessments of functional capacity in patients with heart failure. This calls for a greater use of objective measurements in clinical decision-making based on functional capacity and for preference of direct VO2peak values over subjective NYHA categories. Medication adherence did not significantly alter the subjective-objective NYHA trends.

Název v anglickém jazyce

Relationship between Functional Capacity and Medication Adherence in Heart Failure

Popis výsledku anglicky

This study investigated the relationship between the subjective New York Heart Association (NYHA) class and objective exercise capacity (VO2peak) in patients with heart failure and whether it is influenced by medication adherence. Methods: Data from 170 heart failure patients in the Level-CHF register were analysed, and adherence was assessed by serum drug level testing. Objective exercise capacity was assessed by cardiopulmonary exercise testing using a bicycle ergometer. Results: Objective VO2peak frequently exceeded the subjective NYHA class with 46% concordance, especially at the extreme ends of the spectrum. Minor differences in subjective NYHA class in relation to medication adherence were noted, but no substantial disparity was observed. Conclusion: These findings highlight the discrepancies between subjective and objective assessments of functional capacity in patients with heart failure. This calls for a greater use of objective measurements in clinical decision-making based on functional capacity and for preference of direct VO2peak values over subjective NYHA categories. Medication adherence did not significantly alter the subjective-objective NYHA trends.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10606 - Microbiology

Projekt

<a href="/cs/project/LM2018131" target="_blank" >LM2018131: Česká národní infrastruktura pro biologická data</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Cor et Vasa

ISSN

0010-8650

e-ISSN

—

Svazek periodika

65

Číslo periodika v rámci svazku

Supplement 3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

7

Strana od-do

37-43

Kód UT WoS článku

001147737400001

EID výsledku v databázi Scopus

2-s2.0-85180110242