Hostile Environments: Modifying Surfaces to Block Microbial Adhesion and Biofilm Formation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F25%3A00637067" target="_blank" >RIV/61388971:_____/25:00637067 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11310/25:10499176

Výsledek na webu

<a href="https://www.mdpi.com/2218-273X/15/6/754" target="_blank" >https://www.mdpi.com/2218-273X/15/6/754</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/biom15060754" target="_blank" >10.3390/biom15060754</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Hostile Environments: Modifying Surfaces to Block Microbial Adhesion and Biofilm Formation

Popis výsledku v původním jazyce

Since the first observations of biofilm formation by microorganisms on various surfaces more than 50 years ago, it has been shown that most ´unicellular´ microorganisms prefer to grow in multicellular communities that often adhere to surfaces. The microbes in these communities adhere to each other, produce an extracellular matrix (ECM) that protects them from drugs, toxins and the host's immune system, and they coordinate their development and differentiate into different forms via signaling molecules and nutrient gradients. Biofilms are a serious problem in industry, agriculture, the marine environment and human and animal health. Many researchers are therefore investigating ways to disrupt biofilm formation by killing microbes or disrupting adhesion to a surface, quorum sensing or ECM production. This review provides an overview of approaches to altering various surfaces through physical, chemical or biological modifications to reduce/prevent microbial cell adhesion and biofilm development and maintenance. It also discusses the advantages and disadvantages of each approach and the challenges faced by researchers in this field.

Název v anglickém jazyce

Hostile Environments: Modifying Surfaces to Block Microbial Adhesion and Biofilm Formation

Popis výsledku anglicky

Since the first observations of biofilm formation by microorganisms on various surfaces more than 50 years ago, it has been shown that most ´unicellular´ microorganisms prefer to grow in multicellular communities that often adhere to surfaces. The microbes in these communities adhere to each other, produce an extracellular matrix (ECM) that protects them from drugs, toxins and the host's immune system, and they coordinate their development and differentiate into different forms via signaling molecules and nutrient gradients. Biofilms are a serious problem in industry, agriculture, the marine environment and human and animal health. Many researchers are therefore investigating ways to disrupt biofilm formation by killing microbes or disrupting adhesion to a surface, quorum sensing or ECM production. This review provides an overview of approaches to altering various surfaces through physical, chemical or biological modifications to reduce/prevent microbial cell adhesion and biofilm development and maintenance. It also discusses the advantages and disadvantages of each approach and the challenges faced by researchers in this field.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10606 - Microbiology

Projekt

<a href="/cs/project/EH22_008%2F0004573" target="_blank" >EH22_008/0004573: Průlomové laserové technologie pro chytrou výrobu, vesmírné a biotechnologické aplikace</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biomolecules

ISSN

2218-273X

e-ISSN

2218-273X

Svazek periodika

15

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

28

Strana od-do

754

Kód UT WoS článku

001516110900001

EID výsledku v databázi Scopus

2-s2.0-105009118900