Cutaneous histoplasmosis in a roadkill European badger (Meles meles), Czech Republic

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F25%3A00643056" target="_blank" >RIV/61388971:_____/25:00643056 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62157124:16170/25:43882409 RIV/62157124:16270/25:43882409 RIV/62157124:16810/25:43882409

Výsledek na webu

<a href="https://actavet.vfu.cz/94/3/0187/" target="_blank" >https://actavet.vfu.cz/94/3/0187/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2754/avb202594030187" target="_blank" >10.2754/avb202594030187</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Cutaneous histoplasmosis in a roadkill European badger (Meles meles), Czech Republic

Popis výsledku v původním jazyce

Histoplasmosis is caused by a thermally dimorphic ascomycete fungus, Histoplasma capsulatum. Europe has long been considered a non-endemic area for histoplasmosis, however, in recent decades, sporadic cases of histoplasmosis have been confirmed in the European badger (Meles meles) in Austria, Denmark, Germany and Switzerland. In 2014, an adult male badger carcass was found on a highway on the outskirts of the city of Brno (Southern Moravia, Czech Republic). A gross pathological examination revealed a good overall body condition prior to receiving multiple traumatic injuries from a car impact. However, multiple irregular nodular lesions measuring up to 5 cm in diameter were observed on the skin of the ventral part of the body and the thoracic limbs. Histopathology revealed a granulomatous inflammatory reaction in the lesions, with abundant macrophages multifocally forming large multinucleated giant cells, lymphocytes, plasma cells and scarce granulocytes. The macrophages contained oval to spherical 2.5-3.0 mu m yeast-like structures in the cytoplasm. These stained mildly to moderately with haematoxylin and eosin and well with periodic acid Schiff, revealing a small central nucleus surrounded by a clear zone. Other organs showed no macroscopic or microscopic pathology. The internal transcribed spacer rDNA sequence from the skin was identical to a sequence previously detected in a H. capsulatum-infected badger in Germany. This case report detailing cutaneous histoplasmosis in a European badger marks the first documentation of H. capsulatum in the Czech Republic and emphasises the potential for early detection of new and emerging pathogens through wildlife disease monitoring.

Název v anglickém jazyce

Cutaneous histoplasmosis in a roadkill European badger (Meles meles), Czech Republic

Popis výsledku anglicky

Histoplasmosis is caused by a thermally dimorphic ascomycete fungus, Histoplasma capsulatum. Europe has long been considered a non-endemic area for histoplasmosis, however, in recent decades, sporadic cases of histoplasmosis have been confirmed in the European badger (Meles meles) in Austria, Denmark, Germany and Switzerland. In 2014, an adult male badger carcass was found on a highway on the outskirts of the city of Brno (Southern Moravia, Czech Republic). A gross pathological examination revealed a good overall body condition prior to receiving multiple traumatic injuries from a car impact. However, multiple irregular nodular lesions measuring up to 5 cm in diameter were observed on the skin of the ventral part of the body and the thoracic limbs. Histopathology revealed a granulomatous inflammatory reaction in the lesions, with abundant macrophages multifocally forming large multinucleated giant cells, lymphocytes, plasma cells and scarce granulocytes. The macrophages contained oval to spherical 2.5-3.0 mu m yeast-like structures in the cytoplasm. These stained mildly to moderately with haematoxylin and eosin and well with periodic acid Schiff, revealing a small central nucleus surrounded by a clear zone. Other organs showed no macroscopic or microscopic pathology. The internal transcribed spacer rDNA sequence from the skin was identical to a sequence previously detected in a H. capsulatum-infected badger in Germany. This case report detailing cutaneous histoplasmosis in a European badger marks the first documentation of H. capsulatum in the Czech Republic and emphasises the potential for early detection of new and emerging pathogens through wildlife disease monitoring.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

40301 - Veterinary science

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta veterinaria Brno

ISSN

0001-7213

e-ISSN

1801-7576

Svazek periodika

94

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

6

Strana od-do

187-192

Kód UT WoS článku

001600618100003

EID výsledku v databázi Scopus

2-s2.0-105020306255