Recommended Nuclear Data for the Production of Selected Therapeutic Radionuclides

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389005%3A_____%2F19%3A00501158" target="_blank" >RIV/61389005:_____/19:00501158 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1016/j.nds.2019.01.003" target="_blank" >https://doi.org/10.1016/j.nds.2019.01.003</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.nds.2019.01.003" target="_blank" >10.1016/j.nds.2019.01.003</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Recommended Nuclear Data for the Production of Selected Therapeutic Radionuclides

Popis výsledku v původním jazyce

Increasing interest in the treatment of human disease by means of targeted radionuclide-based therapies requires an accurate understanding of achievable yields and quantification of realisable degrees of purity. Important studies within a more extensive Coordinated Research Project of the International Atomic Energy Agency (IAEA CRP) have included in-depth assessments and evaluations of all available measured cross-section data for ten nuclear reactions leading to the formation of Cs-131, Ba-131, Ac-225, Ra-225, Th-227, Ac-227, U-230 and( 230)Pa for various on-going and proposed therapeutic applications in nuclear medicine. Equivalent studies were also undertaken of possible reactions to produce the W-178/low-spin Ta-178m generator system that has been clinically applied in diagnosis by means of SPECT - these particular cross-section studies and recommendations are included in this paper for completeness. All available measured data have been critically reviewed and assessed to produce statistically consistent datasets. Selected datasets have been fitted by a least-squares method with Pade approximations of variable order to evaluate the production cross sections and corresponding uncertainties. New measurements have been made in some instances, and reported data have been adjusted to accommodate new nuclear decay or monitor reaction data which altered the original reported quantities adversely. Insufficient measured data are available in many cases to permit a reliable evaluation of cross sections, and these instances are discussed. Recommended therapeutic radionuclide production reaction data and their uncertainties are available on the Web page of the IAEA Nuclear Data Section at www-nds.iaea.org/radionuclides/ and also at the IAEA medical portal www-nds.iaea.org/medportal/.

Název v anglickém jazyce

Recommended Nuclear Data for the Production of Selected Therapeutic Radionuclides

Popis výsledku anglicky

Increasing interest in the treatment of human disease by means of targeted radionuclide-based therapies requires an accurate understanding of achievable yields and quantification of realisable degrees of purity. Important studies within a more extensive Coordinated Research Project of the International Atomic Energy Agency (IAEA CRP) have included in-depth assessments and evaluations of all available measured cross-section data for ten nuclear reactions leading to the formation of Cs-131, Ba-131, Ac-225, Ra-225, Th-227, Ac-227, U-230 and( 230)Pa for various on-going and proposed therapeutic applications in nuclear medicine. Equivalent studies were also undertaken of possible reactions to produce the W-178/low-spin Ta-178m generator system that has been clinically applied in diagnosis by means of SPECT - these particular cross-section studies and recommendations are included in this paper for completeness. All available measured data have been critically reviewed and assessed to produce statistically consistent datasets. Selected datasets have been fitted by a least-squares method with Pade approximations of variable order to evaluate the production cross sections and corresponding uncertainties. New measurements have been made in some instances, and reported data have been adjusted to accommodate new nuclear decay or monitor reaction data which altered the original reported quantities adversely. Insufficient measured data are available in many cases to permit a reliable evaluation of cross sections, and these instances are discussed. Recommended therapeutic radionuclide production reaction data and their uncertainties are available on the Web page of the IAEA Nuclear Data Section at www-nds.iaea.org/radionuclides/ and also at the IAEA medical portal www-nds.iaea.org/medportal/.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10304 - Nuclear physics

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Nuclear Data Sheets

ISSN

0090-3752

e-ISSN

—

Svazek periodika

155

Číslo periodika v rámci svazku

SI

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

19

Strana od-do

56-74

Kód UT WoS článku

000456611100003

EID výsledku v databázi Scopus

2-s2.0-85060338047