Radioprotective effect of Hydroxyl radical scavengers on prokaryotic and eukaryotic cells under various Gamma irradation conditions

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389005%3A_____%2F19%3A00524442" target="_blank" >RIV/61389005:_____/19:00524442 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1093/rpd/ncz201" target="_blank" >https://doi.org/10.1093/rpd/ncz201</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/rpd/ncz201" target="_blank" >10.1093/rpd/ncz201</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Radioprotective effect of Hydroxyl radical scavengers on prokaryotic and eukaryotic cells under various Gamma irradation conditions

Popis výsledku v původním jazyce

The influence of various hydroxyl radical scavengers such as methanol, ethanol and dimethyl sulfoxide on radiation sensitivity of prokaryotic cells (bacteria Escherichia coli) and eukaryotic cells (yeast Saccharomyces cerevisiae and V79 cells-Chinese hamster pulmonary fibroblasts) irradiated by Co-60 gamma radiation was investigated. The dependence of radiation sensitivity on dose rate in range from 1.8 to 100 Gy h(-1) was evaluated. Survival of cells irradiated by increasing dose rates was followed using clonogenic assay. Specific protective effect was found to be a nonmonotonous function of dose rate with typical maximum at the dose rate range from 50 to 55 Gy h(-1) in all studied cell types.

Název v anglickém jazyce

Radioprotective effect of Hydroxyl radical scavengers on prokaryotic and eukaryotic cells under various Gamma irradation conditions

Popis výsledku anglicky

The influence of various hydroxyl radical scavengers such as methanol, ethanol and dimethyl sulfoxide on radiation sensitivity of prokaryotic cells (bacteria Escherichia coli) and eukaryotic cells (yeast Saccharomyces cerevisiae and V79 cells-Chinese hamster pulmonary fibroblasts) irradiated by Co-60 gamma radiation was investigated. The dependence of radiation sensitivity on dose rate in range from 1.8 to 100 Gy h(-1) was evaluated. Survival of cells irradiated by increasing dose rates was followed using clonogenic assay. Specific protective effect was found to be a nonmonotonous function of dose rate with typical maximum at the dose rate range from 50 to 55 Gy h(-1) in all studied cell types.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10610 - Biophysics

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Radiation Protection Dosimetry

ISSN

0144-8420

e-ISSN

—

Svazek periodika

186

Číslo periodika v rámci svazku

2-3

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

5

Strana od-do

186-190

Kód UT WoS článku

000530582200009

EID výsledku v databázi Scopus

2-s2.0-85082779478