Electromagnetic isotope separation of gadolinium isotopes for the production of Tb-152,Tb-155 for radiopharmaceutical applications

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389005%3A_____%2F20%3A00523770" target="_blank" >RIV/61389005:_____/20:00523770 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1016/j.nimb.2019.07.017" target="_blank" >https://doi.org/10.1016/j.nimb.2019.07.017</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.nimb.2019.07.017" target="_blank" >10.1016/j.nimb.2019.07.017</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Electromagnetic isotope separation of gadolinium isotopes for the production of Tb-152,Tb-155 for radiopharmaceutical applications

Popis výsledku v původním jazyce

A demo experiment was performed at the tandem accelerator of MLL Garching where Tb-152 was produced by irradiating a unique ion-implanted Gd-152 target (>99% enriched) with 8 and 12 MeV protons respectively. At these energies mainly Tb-152 was produced by (p,n) reactions plus a small quantity of Tb-153 by (p,gamma) reactions. Upper limits are derived for co-production of other Tb isotopes. The achieved radionuclidic purity would enable direct use for human applications. Gd isotopes of adequate isotopic enrichment could be separated with the SIDONIE mass separator at CSNSM Orsay and prepared as cyclotron targets suited for high current irradiations. In a demo experiment samples of highly enriched Gd-158 were produced at SIDONIE. The sample purity was characterized by prompt gamma activation analysis at NPI Rez. The neighboring mass Gd-152 was found to be suppressed by three to five orders of magnitude, depending on the sample position in the SIDONIE separator.

Název v anglickém jazyce

Electromagnetic isotope separation of gadolinium isotopes for the production of Tb-152,Tb-155 for radiopharmaceutical applications

Popis výsledku anglicky

A demo experiment was performed at the tandem accelerator of MLL Garching where Tb-152 was produced by irradiating a unique ion-implanted Gd-152 target (>99% enriched) with 8 and 12 MeV protons respectively. At these energies mainly Tb-152 was produced by (p,n) reactions plus a small quantity of Tb-153 by (p,gamma) reactions. Upper limits are derived for co-production of other Tb isotopes. The achieved radionuclidic purity would enable direct use for human applications. Gd isotopes of adequate isotopic enrichment could be separated with the SIDONIE mass separator at CSNSM Orsay and prepared as cyclotron targets suited for high current irradiations. In a demo experiment samples of highly enriched Gd-158 were produced at SIDONIE. The sample purity was characterized by prompt gamma activation analysis at NPI Rez. The neighboring mass Gd-152 was found to be suppressed by three to five orders of magnitude, depending on the sample position in the SIDONIE separator.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10304 - Nuclear physics

Projekt

<a href="/cs/project/LM2015056" target="_blank" >LM2015056: Centrum urychlovačů a jaderných analytických metod</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Nuclear Instruments & Methods in Physics Research Section B

ISSN

0168-583X

e-ISSN

—

Svazek periodika

463

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

4

Strana od-do

111-114

Kód UT WoS článku

000518699900018

EID výsledku v databázi Scopus

2-s2.0-85070238774