Increasing particle therapy biological effectiveness by nuclear reaction-driven binary strategies

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389005%3A_____%2F24%3A00584544" target="_blank" >RIV/61389005:_____/24:00584544 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1201/9781003023920-13" target="_blank" >https://doi.org/10.1201/9781003023920-13</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1201/9781003023920-13" target="_blank" >10.1201/9781003023920-13</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Increasing particle therapy biological effectiveness by nuclear reaction-driven binary strategies

Popis výsledku v původním jazyce

The ultimate goal of any form of curative radiotherapy resides in achieving local tumor control by suppressing the proliferative ability of all clonogenic cancer cells. If, on the one hand, the dosimetric precision inherent to charged particle therapy, in principle, allows to reduce the risk of adverse effects due to unnecessary dose absorbed by healthy tissues and/or organs at risk, on the other hand cancer radio resistance continues to represent a cause for treatment failure, leading to local recurrence, metastases and poor prognostic outlook. In order to grow and spread, cancer cells develop mutations that allow them to escape recognition and elimination by the host's immune system. Immunotherapy has gained importance in cancer treatment due to its potential to recover the individual patient's immune recognition of cancer and develop an acquired immune response against malignant cells in the entire body.

Název v anglickém jazyce

Increasing particle therapy biological effectiveness by nuclear reaction-driven binary strategies

Popis výsledku anglicky

The ultimate goal of any form of curative radiotherapy resides in achieving local tumor control by suppressing the proliferative ability of all clonogenic cancer cells. If, on the one hand, the dosimetric precision inherent to charged particle therapy, in principle, allows to reduce the risk of adverse effects due to unnecessary dose absorbed by healthy tissues and/or organs at risk, on the other hand cancer radio resistance continues to represent a cause for treatment failure, leading to local recurrence, metastases and poor prognostic outlook. In order to grow and spread, cancer cells develop mutations that allow them to escape recognition and elimination by the host's immune system. Immunotherapy has gained importance in cancer treatment due to its potential to recover the individual patient's immune recognition of cancer and develop an acquired immune response against malignant cells in the entire body.

Druh

C - Kapitola v odborné knize

CEP obor

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OECD FORD obor

10304 - Nuclear physics

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Monte Carlo in Heavy Charged Particle Therapy: New Challenges in Ion Therapy

ISBN

978-03-678-9716-1

Počet stran výsledku

24

Strana od-do

191-214

Počet stran knihy

350

Název nakladatele

CRC Press

Místo vydání

Boca Raton

Kód UT WoS kapitoly

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