Small-angle X-ray scattering investigations of biomolecular confinement, loading, and release from liquid-crystalline nanochannel assemblies

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F12%3A00374898" target="_blank" >RIV/61389013:_____/12:00374898 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1021/jz2014727" target="_blank" >http://dx.doi.org/10.1021/jz2014727</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1021/jz2014727" target="_blank" >10.1021/jz2014727</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Small-angle X-ray scattering investigations of biomolecular confinement, loading, and release from liquid-crystalline nanochannel assemblies

Popis výsledku v původním jazyce

This perspective explores the recent progress made by means of small-angle scattering methods in structural studies of phase transitions in amphiphilic liquid-crystalline systems with nanochannel architectures and outlines some future directions. Time-resolved small-angle X-ray scattering enable monitoring of the structural dynamics, the modulation of the nanochannel hydration, as well as the key changes in the soft matter organization upon stimuli-induced phase transitions. They permit establishing ofthe inner nanostructure transformation kinetics and determination of the precise sizes of the hydrophobic membraneous compartments and the aqueous channel diameters in self-assembled architectures. Time-resolved structural studies accelerate novel biomedical, pharmaceutical, and nanotechnology applications of nanochannel soft materials by providing better control of DNA, peptide and protein nanoconfinement, and release from diverse stimuli-responsive nanocarrier systems.

Název v anglickém jazyce

Small-angle X-ray scattering investigations of biomolecular confinement, loading, and release from liquid-crystalline nanochannel assemblies

Popis výsledku anglicky

This perspective explores the recent progress made by means of small-angle scattering methods in structural studies of phase transitions in amphiphilic liquid-crystalline systems with nanochannel architectures and outlines some future directions. Time-resolved small-angle X-ray scattering enable monitoring of the structural dynamics, the modulation of the nanochannel hydration, as well as the key changes in the soft matter organization upon stimuli-induced phase transitions. They permit establishing ofthe inner nanostructure transformation kinetics and determination of the precise sizes of the hydrophobic membraneous compartments and the aqueous channel diameters in self-assembled architectures. Time-resolved structural studies accelerate novel biomedical, pharmaceutical, and nanotechnology applications of nanochannel soft materials by providing better control of DNA, peptide and protein nanoconfinement, and release from diverse stimuli-responsive nanocarrier systems.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CD - Makromolekulární chemie

OECD FORD obor

—

Projekt

—

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Physical Chemistry Letters

ISSN

1948-7185

e-ISSN

—

Svazek periodika

3

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

13

Strana od-do

445-457

Kód UT WoS článku

000299860200030

EID výsledku v databázi Scopus

—