Synthesis of well-defined semitelechelic poly[N-(2-hydroxypropyl)methacrylamide] polymers with functional group at the .alpha.-end of the polymer chain by RAFT polymerization

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F13%3A00391498" target="_blank" >RIV/61389013:_____/13:00391498 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1021/ma400042u" target="_blank" >http://dx.doi.org/10.1021/ma400042u</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1021/ma400042u" target="_blank" >10.1021/ma400042u</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Synthesis of well-defined semitelechelic poly[N-(2-hydroxypropyl)methacrylamide] polymers with functional group at the .alpha.-end of the polymer chain by RAFT polymerization

Popis výsledku v původním jazyce

N-(2-Hydroxypropyl)methacrylamide polymer precursors (pHPMA) with very narrow distribution of molecular weights and polymer chain terminating in a single reactive group have big potential in the synthesis of various polymer drug and gene delivery systems. This paper shows that pHPMA can be prepared by reversible addition-fragmentation chain transfer (RAFT) polymerization; the pHPMAs prepared by RAFT polymerization conducted to high conversions contained at the ?-end of the polymer chain a single functional group originated from both, the chain transfer agent (CTA) and initiator (INI) in ratio depending on polymerization conditions. The well-defined monofunctional pHPMAs with narrow molecular weight distribution and with single reactive group situated at the ?-polymer chain end can be prepared in one step by RAFT polymerization initiated by the tailor-made CTA and INI, both containing the same functional group in their structure. Synthesis of pHPMAs terminating in various reactive group

Název v anglickém jazyce

Synthesis of well-defined semitelechelic poly[N-(2-hydroxypropyl)methacrylamide] polymers with functional group at the .alpha.-end of the polymer chain by RAFT polymerization

Popis výsledku anglicky

N-(2-Hydroxypropyl)methacrylamide polymer precursors (pHPMA) with very narrow distribution of molecular weights and polymer chain terminating in a single reactive group have big potential in the synthesis of various polymer drug and gene delivery systems. This paper shows that pHPMA can be prepared by reversible addition-fragmentation chain transfer (RAFT) polymerization; the pHPMAs prepared by RAFT polymerization conducted to high conversions contained at the ?-end of the polymer chain a single functional group originated from both, the chain transfer agent (CTA) and initiator (INI) in ratio depending on polymerization conditions. The well-defined monofunctional pHPMAs with narrow molecular weight distribution and with single reactive group situated at the ?-polymer chain end can be prepared in one step by RAFT polymerization initiated by the tailor-made CTA and INI, both containing the same functional group in their structure. Synthesis of pHPMAs terminating in various reactive group

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CD - Makromolekulární chemie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Macromolecules

ISSN

0024-9297

e-ISSN

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Svazek periodika

46

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

2100-2108

Kód UT WoS článku

000316847500007

EID výsledku v databázi Scopus

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