In vivo nanotoxicity testing using the zebrafish embryo assay

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F13%3A00394403" target="_blank" >RIV/61389013:_____/13:00394403 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1039/C3TB20528B" target="_blank" >http://dx.doi.org/10.1039/C3TB20528B</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1039/C3TB20528B" target="_blank" >10.1039/C3TB20528B</a>

Jazyk výsledku

angličtina

Název v původním jazyce

In vivo nanotoxicity testing using the zebrafish embryo assay

Popis výsledku v původním jazyce

Nanoparticles are increasingly used for biomedical purposes. Many different diagnostic and therapeutic applications are envisioned for nanoparticles, but there are often also serious concerns regarding their safety. Given the fact that numerous new nanomaterials are being developed every day, and that not much is known about the long-term toxicological impact of exposure to nanoparticles, there is an urgent need to establish efficient methods for nanotoxicity testing. The zebrafish (Danio rerio) embryoassay has recently emerged as an interesting intermediate? method for in vivo nanotoxicity screening, enabling (semi-) high-throughput analyses in a system significantly more complex than cultured cells, but at the same time also less invasive? and lessexpensive than large-scale biocompatibility studies in mice or rats. The zebrafish embryo assay is relatively well-established in the environmental sciences, but has not yet gained wide notice in the nanomedicine field. Using prototypic p

Název v anglickém jazyce

In vivo nanotoxicity testing using the zebrafish embryo assay

Popis výsledku anglicky

Nanoparticles are increasingly used for biomedical purposes. Many different diagnostic and therapeutic applications are envisioned for nanoparticles, but there are often also serious concerns regarding their safety. Given the fact that numerous new nanomaterials are being developed every day, and that not much is known about the long-term toxicological impact of exposure to nanoparticles, there is an urgent need to establish efficient methods for nanotoxicity testing. The zebrafish (Danio rerio) embryoassay has recently emerged as an interesting intermediate? method for in vivo nanotoxicity screening, enabling (semi-) high-throughput analyses in a system significantly more complex than cultured cells, but at the same time also less invasive? and lessexpensive than large-scale biocompatibility studies in mice or rats. The zebrafish embryo assay is relatively well-established in the environmental sciences, but has not yet gained wide notice in the nanomedicine field. Using prototypic p

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CD - Makromolekulární chemie

OECD FORD obor

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Projekt

<a href="/cs/project/GAP301%2F12%2F1254" target="_blank" >GAP301/12/1254: Překonání přirozené a mnohočetné lékové rezistence nádor-selektivní akumulací inhibitorů ABC transportérů/Bcl-2 či léčebného genu pod PEG-3 promotorem</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Materials Chemistry B

ISSN

2050-750X

e-ISSN

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Svazek periodika

1

Číslo periodika v rámci svazku

32

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

8

Strana od-do

3918-3925

Kód UT WoS článku

000322177800006

EID výsledku v databázi Scopus

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